Results 151 to 160 of about 34,442 (247)
Mesenchymal Stromal Cell Rejuvenation Strategies to Enhance Clinical Translation in Cell Therapy
MSC rejuvenation strategies and functional outcomes. Aging‐associated alterations in MSCs, including increased IL‐6/IL‐8 secretion, ROS accumulation, epigenetic drift, and mitochondrial dysfunction, impair stemness. Rejuvenation approaches, epigenetic modulation (VPA, AZAc, OSKM, TERT), metabolic interventions (resveratrol, calcitriol, NMD, asprosin ...
Astrid Sodomaco +8 more
wiley +1 more source
Measuring hierarchical structure across hominid percussive tool-use sequences. [PDF]
Taylor D +3 more
europepmc +1 more source
This study highlights the importance of the unprotected Yabassi Key Biodiversity Area, Cameroon, for primate conservation in the Gulf of Guinea biodiversity hotspot. We modelled primate distribution patterns and found that historically overlooked parts of the landscape have high species richness and are critical for some threatened species.
Vianny Rodel Vouffo Nguimdo +4 more
wiley +1 more source
In Vitro Massively Parallel Screening of Human Regulatory Elements Involved in Postcranial Skeletal Development for Differential Activity Compared to Chimpanzee. [PDF]
Okamoto AS +3 more
europepmc +1 more source
Animal Social Network Structures Across the Fast‐Slow Continuum
Using a mathematical model, we examine how the rate of demographic replacement (represented by generation time) influences emergent social network structure in natural populations. By considering a range of social preferences and modes of social inheritance, we find that demographic replacement influences the extent to which social networks can self ...
Ross S. Walker +4 more
wiley +1 more source
Chimpanzee culture beyond the conspicuous: Evidence for broad-scale observational social learning in wild individuals. [PDF]
Slania NE +8 more
europepmc +1 more source
Male vervet monkeys were more likely to lead group progressions than females or juveniles, especially during potentially riskier crossing situations, i.e., rivers. Dominant males who had not yet sired offspring were the most likely to lead progressions.
Josefien A. Tankink +3 more
wiley +1 more source
Female Affiliation and Status in Semi-Free-Ranging Chimpanzees. [PDF]
Bryer MAH +18 more
europepmc +1 more source
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Climate change is increasingly impacting arboreal mammals, yet these effects vary across regions and taxa, and global syntheses to inform conservation priorities remain limited. This study presents the first global synthesis of climate change impacts on arboreal mammals using a systematic review, meta‐analysis, and bibliometric analysis.
Dinayadura Kalathma Navanjalie Samanthi De Silva +2 more
wiley +1 more source

