Results 131 to 140 of about 98,552 (325)
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
The FEBS Journal, EarlyView.Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Ibis, EarlyView.Human‐induced environmental change is reshaping plant communities, requiring native animals to adapt their foraging behaviour to track and exploit novel food resources. Trees such as pines (Pinus spp.) introduced for plantation forestry outside of their native ranges often become naturalized.
Tirth Vaishnav +2 more
wiley +1 more source
Journal of Anatomy, EarlyView.Aging of bone density (BV/TV) is regional: Forelimb [left] elements gain bone sporadically (orange) but hind limb elements [right] lose bone globally (blue). Abstract Globally, human population structure is quickly trending older, increasing the prevalence and systemic burden of age‐related skeletal disorders such as osteoporosis.
Cassandra M. Turcotte +16 more
wiley +1 more source
The raphe nuclear organization and serotonergic system in the bat (Artibeus planirostris)
Journal of Anatomy, EarlyView.Schematic representation of the methodological workflow used to characterize the serotonergic (5‐HT) system in the bat Artibeus planirostris. Serotonin (5‐HT) immunohistochemistry was performed on brainstem sections to identify and map the distribution of serotonergic neurons within the raphe nuclei.
Mariana D. Leite +9 more
wiley +1 more source
Journal of Anatomy, EarlyView.Variation in arboreality across gorilla populations is associated with systematic differences in manual digital lengths. Using a new dataset of linear metrics from the Bwindi mountain gorillas, we quantify metacarpal and phalangeal lengths in eastern and western gorilla populations across all five rays. Consistent with quantified behavioral differences,
Elliot G. Greiner +16 more
wiley +1 more source
Long-term effects of infant attachment organization on adult behavior and health in nursery-reared, captive chimpanzees (Pan troglodytes) [PDF]
, 2015 Bard, Kim +4 more
core +2 more sources
Functional morphology of trabecular bone in the calcaneus of African apes
Journal of Anatomy, EarlyView.Pan exhibits significantly higher calcaneal tuberosity trabecular thickness (Tb.Th) and bone volume fraction (BV/TV) than Gorilla, potentially reflecting higher triceps surae forces for vertical climbing. Both taxa have significantly higher Tb.Th and BV/TV in the anterior calcaneus; the difference is exaggerated in Gorilla, potentially reflecting ...
Christine M. Harper, Biren A. Patel
wiley +1 more source