Results 21 to 30 of about 6,119,270 (311)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Effect of Dried Porcine Placenta on Growth Performance in Post-Weaning Pigs

open access: yesWalailak Journal of Science and Technology, 2011
The objective of this research was to investigate the effect of substituting fish meal with dried porcine placenta (DPP) on the growth performance in post-weaning pigs. The experimental animals included 25 males and 25 females.
China SUPAKORN, Siripen THONGPASSANO
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Preface: Morphology and Internal Mixing of Atmospheric Particles

open access: yesAtmosphere, 2018
n ...
Swarup China, Claudio Mazzoleni
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Genetic parameter estimates for weaning weight and Kleiber ratio in goats [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2012
The research was conducted to evaluate the factors affecting on weaning weight (WW) and Kleiber ratio (KR) and toestimate genetic parameters for two traits in goats.
China Supakorn, Winai Pralomkarn
doaj  

Epilogue to “Islam in China/China in Islam” [PDF]

open access: yesCross-Currents: East Asian History and Culture Review, 2015
Author(s): Lipman, Jonathan | Abstract: In my opening comments during the conference “The Everyday Life of Islam: Focus on Islam in China,” held at Cornell University on April 27 and 28, 2012, I proposed a number of themes, tensions, and conflicts on which we might focus our discussion of the papers.
openaire   +2 more sources

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