Results 21 to 30 of about 6,119,270 (311)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Effect of Dried Porcine Placenta on Growth Performance in Post-Weaning Pigs
The objective of this research was to investigate the effect of substituting fish meal with dried porcine placenta (DPP) on the growth performance in post-weaning pigs. The experimental animals included 25 males and 25 females.
China SUPAKORN, Siripen THONGPASSANO
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Preface: Morphology and Internal Mixing of Atmospheric Particles
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Swarup China, Claudio Mazzoleni
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Genetic parameter estimates for weaning weight and Kleiber ratio in goats [PDF]
The research was conducted to evaluate the factors affecting on weaning weight (WW) and Kleiber ratio (KR) and toestimate genetic parameters for two traits in goats.
China Supakorn, Winai Pralomkarn
doaj
Epilogue to “Islam in China/China in Islam” [PDF]
Author(s): Lipman, Jonathan | Abstract: In my opening comments during the conference “The Everyday Life of Islam: Focus on Islam in China,” held at Cornell University on April 27 and 28, 2012, I proposed a number of themes, tensions, and conflicts on which we might focus our discussion of the papers.
openaire +2 more sources

