Results 31 to 40 of about 94,948 (243)

Protection and enlightenment of ecological integrity of Canadian national parks [PDF]

E3S Web of Conferences, 2019
Canada is one of the first countries in the world to establish a national park, and pioneered the concept of ecological integrity management of national parks.
Yang Shuhui, Duan Xiaoyu
doaj   +1 more source

Dilemma Faced by Management Staff in China’s Protected Areas

Land, 2021
Protected areas (PAs) are designated to safeguard specific areas with natural and cultural values. Importantly, appropriate management is vital for PAs to achieve their conservation goals. Therefore, the management staff is essential for guaranteeing the
Liang Chang, Teiji Watanabe
doaj   +1 more source

Effects of Soundscapes on Human Physiology and Psychology in Qianjiangyuan National Park System Pilot Area in China

Forests, 2022
The development of China’s national parks is still in the initial stage, and few scholars have studied the effects of soundscapes on human physiology and psychology from the perspective of the auditory senses in national parks. In this study, the Qianjiangyuan National Park System Pilot Area was taken as the research subject, physiological indicators ...
Peng Wang, Youjun He, Wenjuan Yang, Nan Li, Jiaojiao Chen   +4 more
openaire   +1 more source

Survey, Research And Prospect Of Signage Systems In National Parks In Yunnan Province

MATEC Web of Conferences, 2018
The Signage System is essential to establishing a national park. The authors conducted surveys, analysis and research of identification signs, informational sign, directional signs and functional signs from the signage systems adopted by five national ...
wenjuan XU, shengxi FAN
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Conservation versus development: Uncovering divergent viewpoints of conservationists on National Parks system by Q methodology in China

Global Ecology and Conservation, 2022
Currently, there is a great challenge for the Global South to strengthen protected areas for conservation, as there remain debates on the trade-off and synergies between conservation and human well-being. Differing from existing knowledge generated from individual case-studies with local specificities, this research applied Q methodology to capture the
Jun He, Weijia Zhou
openaire   +2 more sources

Moving toward a Greener China: Is China’s National Park Pilot Program a Solution?

Land, 2020
National parks have been adopted for over a century to enhance the protection of valued natural landscapes in countries worldwide. For decades, China has emphasized the importance of economic growth over ecological health to the detriment of its ...
Gonghan Sheng, Heyuan Chen, Kalifi Ferretti-Gallon, John L. Innes, Zhongjun Wang, Yujun Zhang, Guangyu Wang   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source