Results 41 to 50 of about 95,135 (243)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Moving toward a Greener China: Is China’s National Park Pilot Program a Solution?
Land, 2020 National parks have been adopted for over a century to enhance the protection of valued natural landscapes in countries worldwide. For decades, China has emphasized the importance of economic growth over ecological health to the detriment of its ...
Gonghan Sheng +6 more
doaj +1 more source
Global Ecology and Conservation, 2022 Currently, there is a great challenge for the Global South to strengthen protected areas for conservation, as there remain debates on the trade-off and synergies between conservation and human well-being. Differing from existing knowledge generated from individual case-studies with local specificities, this research applied Q methodology to capture the
Jun He, Weijia Zhou
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Land, 2022 Management evaluation is increasingly required for national parks worldwide as it is an essential mechanism for improving management levels and achieving management objectives. The management capacity evaluation (MCE), an integral component of management
Xianyang Liu, Qingwen Min, Wenjun Jiao
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
OPERATION OF NEW AND HIGH-TECH DEVELOPMENT ZONE – “CHINA-SINGAPORE SUZHOU INDUSTRIAL PARK”
Наука и техника, 2017 Systematic work of the higher authorities of China on achievement and implementation of generally valid aims in the field of science and technology allowed the People’s Republic of China to reach intense innovative advancement of its conomy. New and High-
Qi Ji., Yu. G. Aliakseyeu
doaj +1 more source