Results 71 to 80 of about 1,402 (185)

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Machine Learning Paradigm for Advanced Battery Electrolyte Development

Carbon Energy, EarlyView.
Electrolyte materials determine ion transport kinetics within the bulk and interphases, ultimately influencing the performance of battery systems. As data‐driven paradigms increasingly reshape materials discovery, this review provides an application‐oriented exploration of the intersection between machine learning and electrolyte science. By evaluating
Chang Su, Mengfan Pei, Keyu Chen, Xigao Jian, Fangyuan Hu   +4 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

How I Do It: Two Novel, Low‐Cost Phonomicrosurgery Models With Open‐Source, 3D‐Printed Laryngoscopes

The Laryngoscope, EarlyView.
Two new vocal fold microflap models using products found in any grocery store have been developed along with publicly available 3D‐printable parts for simulating multiple laryngoscopes commonly used during laryngeal phonomicrosurgery. This represents a low cost, easily reproducible model for basic laryngeal phonomicrosurgery training.
Sapir Pinhas, Ari D. Schuman, Itamar Pinhas, Aaron D. Friedman   +3 more
wiley   +1 more source

Review of the Progressing Role of Solar Photovoltaics in Energy Transition Scenarios Over Five Decades of 100% Renewable Energy Systems Research

Progress in Photovoltaics: Research and Applications, EarlyView.
Over the last five decades, several milestones in energy system modelling enabled the progressing role of solar PV in the field of 100% renewable energy systems research. The key advancements are grouped into visionary scoping, advances in PV system applications, expanding economic insights, methodological advances and additional aspects. ABSTRACT Five
Christian Breyer, Siavash Khalili, Dennis Bredemeier, Arnulf Jäger‐Waldau, Dominik Keiner, Marta Victoria   +5 more
wiley   +1 more source

A Droplet‐Microarray Platform for Multiplex Profiling of Breast Cancer Exosome Subtypes in Patients’ Blood Plasma Samples

Small, EarlyView.
This study presents a droplet‐microarray platform integrated with a DNase I‐assisted MoS2 FRET aptasensor for multiplexed profiling of breast cancer subtypes’ exosomes from patients’ plasma. By targeting HER2, MUC1, and CD44, the system enables sensitive detection and accurate discrimination of luminal A, HER2‐positive, and triple‐negative subtypes ...
Yi Liu, Ruolin Zhang, Jialei Song, Meng Xiao, Yue Meng, Zhiyang Li, Jingyu Shi, Yunyan Tai, Bing Gu, Mo Yang   +9 more
wiley   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Vision language models for bridge inspections: A review of applications in image‐based damage documentation

Structural Concrete, EarlyView.
Abstract Automating bridge inspections requires more than detecting individual damage instances. It demands systems capable of describing, contextualizing, and interpreting damage in an inspection‐relevant manner. Conventional computer vision approaches, such as object detection and segmentation, primarily address visual recognition tasks and are ...
Rona Firdes Çelik, Ulas Bagci, Sylvia Kessler   +2 more
wiley   +1 more source

Vibratory Characteristics and Quantitative Parameters of Laryngeal Dystonia: A Scoping Review of High‐Speed Videoendoscopy Studies

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To review the clinical application and quantitative parameters of high‐speed videoendoscopy (HSV) in evaluating vocal fold kinematics in patients with laryngeal dystonia (LD), to summarize the limitations of existing studies, and to provide a reference for future clinical standardization.
Yuan‐Jia Hu, Jia Song, Sen‐Nian Zheng, Lu Xing, Yu‐Jie Feng, Sheng‐Tao Wu, Shu‐Yi Zeng, Ying‐Shan Tan, Qiu‐Tong Chen, Pei‐Yun Zhuang   +9 more
wiley   +1 more source

Image and video analysis using graph neural network for Internet of Medical Things and computer vision applications

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Graph neural networks (GNNs) have revolutionised the processing of information by facilitating the transmission of messages between graph nodes. Graph neural networks operate on graph‐structured data, which makes them suitable for a wide variety of computer vision problems, such as link prediction, node classification, and graph classification.
Amit Sharma, Ashutosh Sharma, Alexey Tselykh, Alexander Bozhenyuk, Byung‐Gyu Kim   +4 more
wiley   +1 more source