Results 21 to 30 of about 1,679 (149)

Whole-genome sequencing of Chinese centenarians reveals important genetic variants in aging WGS of centenarian for genetic analysis of aging. [PDF]

Hum Genomics, 2020
Abstract Background Genetic research on longevity has provided important insights into the mechanism of aging and aging-related diseases. Pinpointing import genetic variants associated with aging could provide insights for aging research. Methods We performed a whole-genome sequencing in 19 centenarians to establish the genetic basis of human ...
Shen S, Li C, Xiao L, Wang X, Lv H, Shi Y, Li Y, Huang Q.   +7 more
europepmc   +5 more sources

Arthritis, Other Medical Illnesses and Morale Among Chinese Nonagenarians and Centenarians

International Journal of Gerontology, 2017
Background: Limited studies have explored the impact of arthritis, other medical illnesses on morale in the elderly. Our study is aim to assess the association between arthritis and morale among Chinese nonagenarians and centenarians.
Yingying Cai, Han Wang, Birong Dong, Lei Zhang, Juelin Deng   +4 more
doaj   +2 more sources

Relationships of Lipids Profile with Health-Related Quality of Life in Chinese Centenarians. [PDF]

J Nutr Health Aging, 2020
With the acceleration of the process of aging population, to enjoy a higher health-related quality of life (HRQoL) is the goal of the elderly population and public health. Studies on relationship between HRQoL and lipid profile through a large sample of representative elderly population are scare.This study was conducted to firstly explore the ...
Wang S, Yang S, Jia W, Cao W, Han K, Liu M, He Y.   +6 more
europepmc   +3 more sources

Sex, Residence and Fish Intake Predict Vitamin D Status in Chinese Centenarians. [PDF]

J Nutr Health Aging, 2019
This study aims to investigate the prevalence of vitamin D deficiency in Chinese centenarians and to identify the factors associated with vitamin D deficiency.Cross-sectional population-based study.Hainan province in the south of China.943 subjects aged 100 years old and older.Details on sociodemographics and lifestyle characteristics were collected ...
Yao Y, Fu S, Li N, Hu F, Zhang H, Zhu Q, Luan F, Zhang F, Zhao Y, He Y.   +9 more
europepmc   +3 more sources

Functional disability and depressive symptoms among centenarians in Nanjing, China: the mediating role of leisure activities and attitudes toward aging [PDF]

BMC Psychology
Objective This study examines the association between functional disability and depressive symptoms among Chinese centenarians, and the mediating role of leisure activities and attitudes toward aging in this association.
Xin Xu, Yaolin Pei, Yuan Zhao, Bei Wu
doaj   +2 more sources

Analysis of chronic kidney disease staging with different estimated glomerular filtration rate equations in Chinese centenarians [PDF]

Chinese Medical Journal, 2019
. Background:. Accurate estimation of the glomerular filtration rate (GFR) and staging of chronic kidney disease (CKD) are important. Currently, there is no research on the differences in several estimated GFR equations for staging CKD in a large sample ...
Qiu-Xia Han, Dong Zhang, Ya-Li Zhao, Liang Liu, Jing Li, Fu Zhang, Fu-Xin Luan, Jia-Yu Duan, Zhang-Suo Liu, Guang-Yan Cai, Xiang-Mei Chen, Han-Yu Zhu, Xin Chen   +12 more
doaj   +2 more sources

Cigarette smoking and its association with serum lipid/lipoprotein among Chinese nonagenarians/centenarians [PDF]

Lipids in Health and Disease, 2012
Objective Cigarette smoking had been confirmed as an increased risk for dyslipidemia, but none of the evidence was from long-lived population. In present study, we detected relationship between cigarette smoking habits and serum lipid/lipoprotein (serum ...
Yan-Ling Zhang, Dong-Qing Zhao, Chang-Quan Huang, Bi-Rong Dong   +3 more
doaj   +3 more sources

Sarcopenia as a predictor of mortality in centenarians: insights from a prospective cohort study [PDF]

BMC Geriatrics
Background & aims Centenarians represent a unique population where predictors of mortality are understudied.Studies have shown that sarcopenia is associated with adverse health outcomes and premature death in elderly patients. The aim of our study was to
Yun Tang, Hongyan Lin, Meijuan Chen, Yuanyuan Zhong, Xiaochu Wu, Li Wang   +5 more
doaj   +2 more sources

The relationship between vitamin D levels and Alzheimer’s disease risk: insights from a centenarian study of Chinese women [PDF]

Frontiers in Nutrition
BackgroundWhile vitamin D₃ (VD₃) has been implicated in Alzheimer’s disease (AD) prevention, limited evidence exists among centenarians—particularly women—who exhibit unique cognitive aging trajectories.
Yupeng Li, Xujie Wang, Mei Yu, Fei Wang, Dong Song, Musong Liu, Xu Liang, Hongzhou Liu, Jiangbo Liu, Shihui Fu, Shihui Fu, Xuhui Liu   +11 more
doaj   +2 more sources

The Immune Cell Atlas of "Longevity Molecular Tag": Identification of Principal Immune Cell Subsets and Their Underlying Molecular Regulatory Mechanisms. [PDF]

Aging Cell
This study aims to develop an immune cell atlas of the “Longevity Molecular Tags” by employing the Scissor algorithm to identify key immune cell subsets associated with longevity phenotypes. Subsequently, the underlying immune molecular mechanisms contributing to the longevity‐associated immune cell subsets were investigated through differential gene ...
Zhang Z, Su H, Fu S, Ji F, Liang L, Song W, Hu C, Wei L, Long E, Lin Y, Ni X.   +10 more
europepmc   +2 more sources