Results 61 to 70 of about 1,679 (149)
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu +8 more
wiley +1 more source
Frontiers in Medicine, 2021 Background: Frailty is an epidemic age-related syndrome addressing heavy burden to the healthcare system. Subject to the rarity, age-, and gender-specific prevalence of frailty and its prognosis among the longevous population remains under-investigated ...
Huai-yu Wang +8 more
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Advanced Science, Volume 13, Issue 4, 19 January 2026.Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao +13 more
wiley +1 more source
ENVIRONMENTAL MECHANISM OF REGIONAL LONGEVITY IN CHINA
Geography, Environment, Sustainability, 2015 The integrated study on environment of typical China’s longevity areas was conducted by using comprehensive methods of health geography. It was found that Chinese longevity areas mainly located in the south China and clustered in Sichuan-Chongqing ...
Wuyi Wang +5 more
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Sex hormones and physical function among the Chinese oldest-old and centenarian women
Journal of Translational Medicine, 2022 Abstract Background Physical independence is crucial for overall health in the elderly individuals. The life expectancy of women has been shown to be higher than that of men, which is also known as the “male–female health-survival paradox”. Sex hormones may be one of the explanations.
Qiao Zhu +7 more
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Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review
Medicine Bulletin, Volume 2, Issue 1, Page 94-123, January 2026.ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng +8 more
wiley +1 more source
Successful Aging among Chinese centenarians in Hong Kong: A multidimensional approach [PDF]
The Gerontologist, 2015 First Session: Latest results from centenarian’s ...
Lau, HP, Cheung, KSL, Kwan, SKJ
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Clinical Interventions in Aging, 2020 Shengshu Wang,1 Miao Liu,1,2 Shanshan Yang,1 Jianhua Wang,1,2 Wangping Jia,1 Wenzhe Cao,1 Ke Han,1 Yao He1,2 1Institute of Geriatrics, The 2nd Medical Center, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for ...
Wang S +7 more
doaj
Reflections on Gerontological Nursing Over the Past 50 Years
Journal of Advanced Nursing, EarlyView.
Wendy Moyle
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The mechanisms in glucose metabolism of aging hippocampus
Ibrain, Volume 11, Issue 4, Page 457-475, Winter 2025.Cognitive decline in elders stems from the irreversible loss and functional decline of neurons, with the hippocampus being particularly susceptible to age‐related neuronal deterioration. Glucose acts as the primary fuel for the brain, and a constant provision of glucose to the hippocampus is essential for memory and cognitive functions.
Rui He +6 more
wiley +1 more source