Results 81 to 90 of about 1,679 (149)

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, Volume 12, Issue 43, November 20, 2025.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

Irisin, the Myokine: Guardian and Mediator in Cardiovascular System

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 6, November 2025.
This graphical abstract illustrates the interconnections between key cardiovascular and cerebrovascular conditions, along with potential influencing factors. Central to the diagram are several critical pathological states: Atherosclerosis, which is linked to downstream cardiovascular events such as myocardial infarction and myocardial ischemia ...
Tian Lan, Xueru Yan, Jie Li, Haoran Gu, Qi Hou, Enpeng He, Qingyuan Yang   +6 more
wiley   +1 more source

Protective Effect of Pediococcus pentosaceus Li05 on Constipation via TGR5/TPH1/5‐HT Activation

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The mechanism of Li05 in alleviating constipation. Li05 intervention regulated gut microbiota and bile acid metabolism, increasing 5‐HT levels through the TGR5/TPH1 activation to ameliorate constipation. ABSTRACT Pediococcus pentosaceus Li05, a strain of lactic acid bacteria isolated from the faeces of healthy volunteers, exhibited potential protective
Hui Chen, Fengjiao Wang, Shengjie Li, Longxian Lv, Hao Xu, Jiafeng Xia, Lvwan Xu, Ding Shi, Lanjuan Li   +8 more
wiley   +1 more source

A Comparative Study on the Health Status and Behavioral Lifestyle of Centenarians and Non-centenarians in Zhejiang Province, China—A Cross-Sectional Study

Frontiers in Public Health, 2019
Background: The growth rate of centenarians was unusually rapid in recent decades, ushering in an era of longevity. This study aims to explore the difference between centenarians and non-centenarians using quantitative research, and to scientifically ...
Chao Rong, Chao Rong, Shu-Hua Shen, Lu-Wei Xiao, Qi Huang, Han-Ti Lu, Hong-Xian Wang, Zheng-Xiang Li, Xiao-Ming Wang   +8 more
doaj   +1 more source

Thyroid nodules in centenarians: prevalence and relationship to lifestyle characteristics and dietary habits

Clinical Interventions in Aging, 2018
Yao Yao,1,* Xianghui Chen,2,* Shengzheng Wu,2 Liang Guo,3 Hao Zhang,4 Qiao Zhu,5 Jie Tang,3 Fuxin Luan,5 Yali Zhao,5 Faqin Lv,2 Yao He1 1Institute of Geriatrics, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for ...
Yao Y, Chen XH, Wu SZ, Guo L, Zhang H, Zhu Q, Tang J, Luan FX, Zhao YL, Lv FQ, He Y   +10 more
doaj  

Cigarette smoking is associated with increased diastolic blood pressure among Chinese nonagenarians/centenarians

Blood Pressure, 2013
Cigarette smoking has been confirmed as a factor influencing arterial blood pressure. In the present study, we studied whether cigarette smoking habits were still associated with arterial blood pressure among Chinese nonagenarians/centenarians.The present study analyzed data from a survey conducted on all residents aged 90 years or more in the ...
Zhao, Dong-Qing, Huang, Chang-Quan, Zhang, Yan-Ling, Dong, Bi-Rong, Liu, Qing-Xiu   +4 more
openaire   +2 more sources

Author Correction: Deep insights into the gut microbial community of extreme longevity in south Chinese centenarians by ultra-deep metagenomics and large-scale culturomics. [PDF]

NPJ Biofilms Microbiomes, 2023
Li C, Luan Z, Zhao Y, Chen J, Yang Y, Wang C, Jing Y, Qi S, Li Z, Guo H, Xu W, Zhao B, Wu C, Wang S, Yang Y, Sun G.   +15 more
europepmc   +1 more source

Waist–Calf Circumference Ratio Is an Independent Risk Factor of HRQoL in Centenarians

Diabetes, Metabolic Syndrome and Obesity, 2020
Shanshan Yang, 1, 2,* Miao Liu, 1,* Shengshu Wang, 1 Wangping Jia, 1 Ke Han, 1 Yao He 1 1Institute of Geriatrics, State Key Laboratory of Kidney Disease, Beijing Key Laboratory of Aging and Geriatrics, The 2nd Clinical Center, Chinese PLA General ...
Yang S, Liu M, Wang S, Jia W, Han K, He Y   +5 more
doaj  

Abstracts of the 18th SCWD Conference, 11‐13 December 2025 in Rome/Italy

JCSM Communications, Volume 9, Issue 1, January/June 2026.
wiley   +1 more source

The Role of BMI and Blood Pressure in the Relationship Between Total Cholesterol and Disability in Chinese Centenarians: A Cross-Sectional Study. [PDF]

Front Med (Lausanne), 2021
Wang S, Jia W, Yang S, Han K, Cao W, Ren X, Li J, Tai P, Kou F, Liu M, He Y.   +10 more
europepmc   +1 more source