Results 71 to 80 of about 181,360 (308)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese

, 2010
Objectives Recent association studies by the Australo-Anglo-American Spondyloarthritis Consortium (TASC) in Caucasian European populations from Australia, North America and the UK have identified a number of genes as being associated with ankylosing ...
Wang, N., P. A. Danoy, Reveille, J. D., M. A. Brown, Danoy, P. A., Jiang, Lei, Ward, M. M., Davidson, Stuart I., Brown, Matthew A., Danoy, PA, Jiang, L, Wordsworth, B. P., Xu, H, H. Xu, Liu, Yu, Sun, Linyun, Jiang, L., Han, H., Savage, L., L. Sun, Han, J, Visscher, P. M., J. Han, Wu, Xin, P. M. Visscher, Davidson, S. I., Visscher, PM, Wu, X., N. Wang, null null, Davidson, SI, Y. Liu, Danoy, Patrick A., Liu, Y, Evans, D. M., L. Jiang, H. Han, Wang, N, Han, Huanxing, Xu, H., Wu, X, Han, H, Han, Jun, Han, J., X. Wu, Xu, Huji, Visscher, Peter M., Thomas, G. P., Sun, L, Liu, Y., S. I. Davidson, Wang, Niansong, Sun, L., Brown, MA, Weisman, M. H., Brown, Matthew A, Thomas, Gethin P., G. P. Thomas, Thomas, GP   +58 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

秉要執本，在乎情性之極： 陸希聲《道德真經傳》「性情論」發微 [PDF]

, 2013
[[issue ...
江淑君, Chiang, Shu-chnu
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Genetic variants and haplotypes of the UGT1A9, 1A7 and 1A1 genes in Chinese Han

Genetics and Molecular Biology, 2012
In this report, we describe combined polymorphisms of the UGT1A9, UGT1A7 and UGT1A1 genes in 100 unrelated, healthy Chinese Han subjects. The functional regions of these genes were sequenced and comprehensively analyzed for genetic polymorphisms.
Xiaoqing Zhang, Guokun Ao, Yuewen Wang, Wei Yan, Min Wang, Erfei Chen, Fangfang Yang, Jin Yang   +7 more
doaj  

Taxonomic studies of parasitic nyctotherans from chinese Anura amphibians III. Wichtermania

, 2002
Wu-Han Xiao, Jian-Guo Wang and Lian-Xiang Li (2002) Taxonomic studies of parasitic nyctotherans from Chinese Anura amphibians III. Wichtermania. Zoological Studies 41(1): 69-76.
Wu-Han Xiao, Jian-Guo Wang and Lian-Xiang Li, Wang, JG, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China   +2 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidemia

Pharmacogenomics and Personalized Medicine
Chao Chen,1,* Yan Tian,2,* Fengshun Jia,1,* Mingkun Feng,1 Guoqiang Zhang,2 Qian Li,2 Yanwei Zhang,3 Ningling Sun,4 Songnian Hu,5,6 Zheng Ji1 1Department of Cardiology, Tangshan Gongren Hospital, Tangshan, Hebei, People’s Republic of China ...
Chen C, Tian Y, Jia F, Feng M, Zhang G, Li Q, Zhang Y, Sun N, Hu S, Ji Z   +9 more
doaj