Results 41 to 50 of about 68,892 (355)

Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF‐β1

Advanced Science, EarlyView.
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng, Lulu Zhang, Yimeng Fan, Sijuan Huang, Qingyu Zhao, Chao Han, Zhihui Hao   +6 more
wiley   +1 more source

Transcriptome analysis reveals the potential mechanism of altering viability, yield, and isoquinoline alkaloids in Coptis chinensis through Cunninghamia lanceolata understory cultivation

Chemical and Biological Technologies in Agriculture
The dried rhizomes of Coptis chinensis hold significance in Chinese medicine. Monocropping C. chinensis under the shade of a manmade scaffold, the primary planting mode, poses a threat to the ecological balance.
Yuanyuan Duan, Jingmao You, Jintao Wang, Tao Tang, Xiaoliang Guo, Fanfan Wang, Xiaoyue Wang, Sen Mu, Qingfang Wang, Xiaofeng Niu, Jie Guo   +10 more
doaj   +1 more source

Bacillus velezensis LT1: a potential biocontrol agent for southern blight on Coptis chinensis

Frontiers in Microbiology
IntroductionSouthern blight, caused by Sclerotium rolfsii, poses a serious threat to the cultivation of Coptis chinensis, a plant with significant medicinal value.
Tao Tang, Tao Tang, Fanfan Wang, Houyun Huang, Jie Guo, Jie Guo, Xiaoliang Guo, Yuanyuan Duan, Xiaoyue Wang, Qingfang Wang, Qingfang Wang, Jingmao You, Jingmao You   +12 more
doaj   +1 more source

Study on the bacteriostatic action of Chinese herbal medicine on avian Trichosporon

Poultry Science, 2020
In this study, a strain of Trichosporon was isolated from white pseudomembranes and ulcers formed on mucous membranes of pigeon bursas and was identified through gene sequencing.
Shuang Zhang, Yu Guo, Qianhui Zhao, Wenhui Xue, Yurong Li, Xianjun Wu, Shuying Huo   +6 more
doaj   +1 more source

Effective common chinese herbal medicines used in treating chronic cholecystitis with liver-gallbladder dampness-heat syndrome: A review of clinical studies in the past 10 years

World Journal of Traditional Chinese Medicine, 2023
The objective of the study is to identify the effective common Chinese herbal medicines used in treating chronic cholecystitis with liver-gallbladder dampness-heat syndrome (CCLGDHS) through reviewing relevant clinical studies published in the past 10 ...
Desmond Wei Kang Tee, Hon Foong Wong
doaj   +1 more source

Cytochrome P450 enzyme mediated herbal drug interactions (Part 2) [PDF]

, 2014
To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St.
Phopin, Kamonrat, Prachayasittikul, Virapong, Wanwimolruk, Sompon   +2 more
core  

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

Role of MicroRNAs Induced by Chinese Herbal Medicines Against Hepatocellular Carcinoma: A Brief Review

Integrative Cancer Therapies, 2018
MicroRNAs (miRNAs) are highly conserved, noncoding small RNAs that regulate gene expression, and consequently several important functions including early embryo development, cell cycle, programmed cell death, cell differentiation, and metabolism.
Ge Guo MS, Juhua Zhou PhD, Xiaogaung Yang BS, Jiang Feng BS, Yanxia Shao MS, Tingting Jia MS, Qingrong Huang MS, Yanmin Li BS, Yin Zhong BS, Prakash S. Nagarkatti PhD, Mitzi Nagarkatti PhD   +10 more
doaj   +1 more source

The Globalization of Traditional Medicines: Perspectives Related to the European Union Regulatory Environment

Engineering, 2019
In the Member States of the European Union (EU), a harmonized legislation on medicinal products has been enforced, which specifically defines herbal medicinal products and traditional herbal medicinal products.
Werner Knoess, Jacqueline Wiesner
doaj   +1 more source