Results 61 to 70 of about 1,545,827 (298)

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

Advanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang, Bo Jin, Shipian Li, Qianxi Ouyang, Yu Xiao, Jiaxin Wen, Yehua Lai, Ping Wang, Yongjun Wang, Xuejun Cui, Weian Zhang, Min Yao   +11 more
wiley   +1 more source

Chromosome-level genome assembly of the wild Chinese yam Dioscorea opposita

Scientific Data
Dioscorea opposita, a perennial dioecious vine endemic to East Asia, holds substantial economic value owing to its dual role as a source of both food and traditional medicine.
Tiegang Yang, Huijun Wang, Peng Wang, Yulong Zhao, Xiangyang Li, Guixia Shi, Tiejun Guo, Jie Tang, Guixiao La   +8 more
doaj   +1 more source

Application of Chinese herbal compound preparation in animal breeding

Siliao yanjiu, 2021
The paper reviews the function of Chinese herbal compound preparation and its application in pig, poultry, cattle, sheep and aquatic animal breeding.
Zhan-qiang HAN, Ji-yuan YANG, Lei HUO, Chang-chun LIU, Ya-jiao MA, Yan-fei MENG   +5 more
doaj  

A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

Advanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan, Junyang Chen, Xingmin Chen, Zengyi Fang, Yuanzhen Mi, Pingjin Zou, Shunlian Fu, Huakang Li, Ke Xu, Bing Lin, Jinyi Lang, Meihua Chen   +11 more
wiley   +1 more source

Integrated multi-omics analysis reveals the molecular mechanism of tuber morphogenesis under different planting densities in yam (Dioscorea opposita Thunb.)

Frontiers in Plant Science
Chinese yam (Dioscorea opposita Thunb.) is a typical medicinal and edible homologous plant, whose tubers are used for food or medicine. The length and thickness of the tubers directly determine their yield and quality.
Peng Wang, Peng Wang, Guixiao La, Guixiao La, Xiangyang Li, Xiangyang Li, Dandan Dai, Dandan Dai, Guixia Shi, Guixia Shi, Yi Wen, Yi Wen, Tiegang Yang, Tiegang Yang   +13 more
doaj   +1 more source

A complicated chinese herbal medicine nephrotoxicity

Saudi Journal of Kidney Diseases and Transplantation, 2020
Chinese herbal medicine is widely used globally. In many instances, it is associated with severe adverse outcomes. We report case of a Chinese herbal nephropathy occurring in a 43-year-old woman showing renal impairment, metabolic acidosis, Stokes - Adams syndrome, hypernatremia, and hypokalemia, characteristics not usually encountered in published ...
Haider Ali Omer Mohamed, Osama Mirghani Osman, Husaam Haider Ali, Mohammed Nasser Asiri, Abdulrhman Ali Hassan, Ibrahim Mohammed Almangah, Abbas Omer Elkarib, Ali AbBshabshe   +7 more
openaire   +3 more sources

Evidence-based toxicity evaluation and scheduling of Chinese herbal medicines

, 2013
Ethnopharmacological relevance: While there is an increasing number of toxicity report cases and toxicological studies on Chinese herbal medicines, the guidelines for toxicity evaluation and scheduling of Chinese herbal medicines are lacking.
Mo, Suilin, Basil D. Roufogalis, Yao, Meicun, Kim, Ellie J., Liu, Zhaolan, Ellie J.Y. Kim, Li, George Q., Roufogalis, Basil D., Johnson Q. Huang, Chen, Yuling, Meicun Yao, Jianping Liu, Li, Kong M., Poon, Josiah, Josiah Poon, George Q. Li, Kelvin Chan, Sui-Lin Mo, Razmovski-Naumovski, Valentina (R16317), Huang, Johnson Q., Yang, Depo, Zhaolan Liu, Chan, Kelvin (R15157), Liu, Jianping, McLachlan, Andrew J., Valentina Razmovski-Naumovski, Depo Yang, Kong M. Li, Andrew J. McLachlan, Yuling Chen   +29 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Chinese herbal medicine for bone health

Pharmaceutical Biology, 2014
Chinese herbal medicine (CHM) has been widely used in clinical practice to treat bone disease for thousands of years. They are cost-effective with fewer side effects and are more suitable for long-term use compared with chemically synthesized medicines.Chinese herbal formula prescribed among the CHMs is safe, and it is an alternative medicine for bone ...
Emmanuel, Mukwaya, Fei, Xu, Man-Sau, Wong, Yan, Zhang   +3 more
openaire   +2 more sources