Results 101 to 110 of about 10,419 (174)

Chemoproteomic discovery of a brain‐penetrant, covalent NLRP3 inhibitor that binds a novel allosteric pocket

British Journal of Pharmacology, Volume 183, Issue 22, Page 6718-6734, November 2026.
NLRP3 is a promising inflammatory target, but existing inhibitors lack diversity and brain penetrance, and none are approved. Using chemoproteomics, we discovered a novel series that binds to Cys463 in a previously uncharacterized pocket. Compounds showed nanomolar potency, brain exposure, and in vivo suppression of IL‐1β, supporting neuroinflammatory ...
Donald C. Rogness, Evelyn P. Sievert, Vincent F. Vartabedian, Steffen M. Bernard, Erick Aitchison, William Tao, Mikaela Lindvall, Jing Qian, Christie L. Eissler, Brian E. Nordin, Benjamin D. Horning, Cian Kingston, Kelsey N. Lamb, Joshua C. Bell, Bingwen Lu, Jonathan Pollock, Jun Shi, Roli Khattri, David S. Weinstein, Matthew P. Patricelli, Brian N. Cook, Gabriel M. Simon   +21 more
wiley   +1 more source

Building a Potemkin village in occupied China: Japan's wartime system of linked trade, 1939–43

The Economic History Review, Volume 79, Issue 4, Page 1327-1345, November 2026.
Abstract The paper discusses the novel but little‐known exchange rate system of Japanese‐occupied North China during the Second Sino‐Japanese War, in which exporters were given the right to import in the form of a piece of yellow paper, which could be sold in the secondary market.
Shinji Takagi
wiley   +1 more source

The Sweetpotato Black Rot Pathogen Ceratocystis fimbriata

Molecular Plant Pathology, Volume 27, Issue 11, November 2026.
We review current knowledge of the soilborne Ceratocystis fimbriata pathogen's biology, epidemiology, virulence and management, and identify priorities for future research. ABSTRACT Black rot, caused by the soilborne fungus Ceratocystis fimbriata, is a major postharvest disease of sweetpotato (Ipomoea batatas) worldwide.
Kelly Avila, Camilo H. Parada‐Rojas, Jack Mascarenhas, Lina M. Quesada‐Ocampo   +3 more
wiley   +1 more source

Characteristics and Superspreading Potential of Andes Virus Person-to-Person Transmission. [PDF]

Emerg Infect Dis
Guo Z, Pan K, Zhao Y, Ali ST, Wang K, Cao L, Cui Z, Liu S, Chong KC, He D, Zhao S, Hao Y.   +11 more
europepmc   +1 more source

Introduction: A Mnemosyne of Art & Science

Renaissance Studies, EarlyView.
Ana Duarte Rodrigues, Luís Campos Ribeiro, Henrique Leitão   +2 more
wiley   +1 more source

Hantavirus outbreak on a cruise ship: Public health challenges. [PDF]

Biosaf Health
Liu B, Yang C, Zhu J, Guo X, Luan J, Ba J.   +5 more
europepmc   +1 more source

Tracing the geopolitical influences on the morphological and functional transformation in Guangdong merchant ships: Knowledge mining from the Ming and Qing maritime archives. [PDF]

PLoS One
Ao J, Zhao M, Li W, Feng S, Ye Z, Xu Z, Ji S.   +6 more
europepmc   +1 more source

Greenland Emissions Contribute to Black Carbon Aerosols in the Arctic Marine Boundary Layer. [PDF]

Environ Sci Technol
Teng X, Du M, Song C, Dai Y, Lal Chandani V, Beddows DCS, Dall'Osto M, Baumgardner D, Harrison RM, Brean J, Yang M, Zhang Y, Li W, Shi Z.   +13 more
europepmc   +1 more source

Mental health of fishermen: current research status and future directions-insights from seafarer studies (a scoping review). [PDF]

Front Public Health
Lin W, Fang Y, Song H.
europepmc   +1 more source

Compliance and non-compliance patterns among listed and non-listed ship recycling facilities: a comparative assessment of 22 facilities evaluated for the EU List. [PDF]

Environ Sci Pollut Res Int
Pereira NN, da Silveira CAM, Dos Santos Paula KC, Diniz CA.   +3 more
europepmc   +1 more source