Results 131 to 140 of about 10,590 (265)

Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium

iMeta, EarlyView.
Bazi Bushen Capsule (BZBS) mitigates age‐related endometrial dysfunction by activating AMPK − SIRT3 signaling. Luteolin, a key bioactive component, restores mitochondrial homeostasis via PINK1/Parkin−mediated mitophagy and Drp1 inhibition, improving endometrial function and fertility potential.
Shangqi Li, Feng Deng, Hongjuan Niu, Meng Li, Zeyang Lin, Jiayi Ma, Yue Wang, Yueqi Leng, Yunlong Hou, Wenwen Cui, Yang Yu, Heng Pan, Ping Zhou, Rong Li   +13 more
wiley   +1 more source

An Immune Microenvironment-Integrated Intestinal-on-a-Chip Model for Investigating Immunopathogenesis in Inflammatory Bowel Disease. [PDF]

Molecules
Ying S, Xu H, Xu Y, Mi X.
europepmc   +1 more source

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

iNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

Targeting MEK2 by paeoniflorin: Mechanism underlying its protection against hypobaric hypoxia-induced lung injury. [PDF]

Acta Pharm Sin B
Zhang B.
europepmc   +1 more source

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

iNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source

Is modernization widening cultural differences? [PDF]

PNAS Nexus
Talhelm T.
europepmc   +1 more source

Towards Water, Food and Energy Security: The Global Challenges and Possible Solutions for a Holistic Vision of Sustainability

Irrigation and Drainage, EarlyView.
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley   +1 more source

Epigenetic precision diagnostics of traditional Chinese medicine (TCM) syndrome differentiation: a pilot study of atrial fibrillation with qi-yin deficiency syndrome based on 5-hydroxymethylcytosine signatures in extracellular vesicle DNA from plasma. [PDF]

Chin Med
Fan S, Chen H, Chen H, Du B, Zhen B, Chen X, Zhang L, Li X, Duolikun M, Chen L, Gao H, Shi S, Zhang X, Wang Y, Hu Y, Lin J.   +15 more
europepmc   +1 more source

Realistic Representation, Dynamic Evolution and Determinants of Institutional Quality in China

International Studies of Economics, EarlyView.
ABSTRACT The paper delves into the role of institutional quality in bolstering China's economic resilience post‐COVID‐19, CITIC‐Entropy. It divides institutions into basic and changeable categories, establishing an index system via the CITIC‐Entropy TOPSIS model.
Susu Wang, Qidi Zhang, Jing Fang
wiley   +1 more source

The evolution of traditional Chinese medicine education policies in China: themes, characteristics, and experiences-a historical institutionalism analysis based on 197 policy texts. [PDF]

Front Public Health
Yang F, Yang T, Li Y, Wang D.
europepmc   +1 more source