Results 41 to 50 of about 1,453,160 (348)

Applications and Prospects of Microfluidic Chips in Orthopaedic Diseases

Frontiers in Materials, 2021
With the advent of an ageing society, bone-related diseases such as osteoporosis have become a major human health issue, and osteolytic lesions caused by cancer bone metastasis have always had a poor prognosis.
Xiran Yang, Xiran Yang, Qiangqiang Tang, Qiangqiang Tang, Qiangqiang Tang, Chen Lai, Kai Wu, Xuetao Shi, Xuetao Shi, Xuetao Shi, Xuetao Shi   +10 more
doaj   +1 more source

Finite Element Modeling and Simulation of Orthogonal Cutting With Multi Layer Coated Tools [PDF]

Engineering and Technology Journal, 2008
This paper focuses on the development of Finite Element Method (FEM) inmodeling and simulation of coated cutting tools with multi-layer coats. A special FiniteElement code called (MSC.MARC mentat) is used in the numerical tests, the results arethen ...
Maan Aabid Tawfiq, Zeena jumaa Ahmed
doaj   +1 more source

Research on Intelligent Voltage Regulation Method Within a Station Based on Multi-Agent Reinforcement Learning

IEEE Access
In response to the issues that existing voltage regulation methods cannot finely perceive the load data within the station area, have low regulation precision, and often use active power regulation leading to high electricity costs for users, a novel ...
Zhe Zheng, Pan Li, Wenpeng Cui, Yu Liu, Mingyang Sun, Yingying Chi, Qingchen Yang, Yuzhe Chen   +7 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Applications of Laboratory-Based Phase-Contrast Imaging Using Speckle Tracking Technique towards High Energy X-Rays

Journal of Imaging, 2018
The recently developed speckle-based technique is a promising candidate for laboratory-based X-ray phase-contrast imaging due to its compatibility with polychromatic X-rays, multi-modality and flexibility.
Tunhe Zhou, Fei Yang, Rolf Kaufmann, Hongchang Wang   +3 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Development of a radiation hard version of the Analog Pipeline Chip APC128 [PDF]

, 2001
The Analog Pipeline Chip (APC) is a low noise, low power readout chip for silicon micro strip detectors with 128 channels containing an analog pipeline of 32 buffers depth.
Ballintijn, Blanquart, Bouhali, Dentan, Eick, Erdmann, Horisberger, Michael Hilgers, Pitzl, Roland Horisberger, van Hunen   +10 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Re-use of commercial microfluidics chips for DNA, RNA, and protein electrophoresis

BioTechniques, 2014
Microfluidics chip technology is a powerful and convenient alternative to agarose gels and PAGE, but costs can be high due to certain chips being non-reusable.
Thi Nguyen, Sukyoung Kwak, Steven J. Karpowicz   +2 more
doaj   +1 more source

A system-on-chip digital pH meter for use in a wireless diagnostic capsule [PDF]

, 2005
This paper describes the design and implementation of a system-on-chip digital pH meter, for use in a wireless capsule application. The system is organized around an 8-bit microcontroller, designed to be functionally identical to the Motorola 6805.
Ali, D., Cumming, D.R.S., Hammond, P.A.
core   +1 more source