Results 51 to 60 of about 3,050,859 (351)

Gas stripping in galaxy groups - the case of the starburst spiral NGC 2276 [PDF]

, 2006
Ram pressure stripping of galactic gas is generally assumed to be inefficient in galaxy groups due to the relatively low density of the intragroup medium and the small velocity dispersions of groups.
J. Rasmussen, J. S. Mulchaey, Quilis, T. J. Ponman   +3 more
core   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Effect of alloy composition on machining parameters and surface quality through comprehensive analysis

Frontier Materials & Technologies
This study examined the influence of alloy composition (mild steel and aluminium) on several machining parameters, such as temperature, cutting force, surface roughness, and chip morphology.
Shailesh Rao A., Srilatha Rao
doaj   +1 more source

Machinability Research on the Micro-Milling for Graphene Nano-Flakes Reinforced Aluminum Alloy

Metals, 2019
In this paper, plain aluminum was chosen as matrix alloy and graphene reinforced aluminum alloy composites was successfully prepared via powder metallurgy approach.
Hao-Bo Na, Lin-Hong Xu, Guang-Chao Han, Shao-Kang Liu, Lu-Hua Lu   +4 more
doaj   +1 more source

Comparative studies of variation in end mill radial rake angle and cutting conditions on cutting force and surface integrity during machining of nimonic 263

Materials Research Express, 2020
Tool nomenclature has a profound effect on the machining of alloys and the cutting force during machining. In this study, the effect of changes in radial rake angle of end mill cutter (+7°,0°, −7°) and machining parameters such as spindle rotational ...
S Gowthaman, T Jagadeesha
doaj   +1 more source

Hubble Space Telescope Observations of NGC 6240: a Case Study of an Ultra-Luminous Infrared Galaxy with Obscured Activity [PDF]

, 2003
We present results from an HST study of the morphology and kinematics of NGC 6240. This merging galaxy with a double nucleus is one of the nearest and best-studied ultraluminous infrared galaxies. HST resolves both nuclei into seperate components.
Barbieri C., Chiaberge M., David Axon, de Jong R. S., J. Christopher Mihos, Joris Gerssen, Joshua E. Barnes, Lars Hernquist, Roeland P. van der Marel, Schulz H., van der Marel R. P., Vignati P.   +11 more
core   +4 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

In Situ TEM Study of the Degradation of PbSe Nanocrystals in Air [PDF]

, 2018
PbSe nanocrystals have attracted widespread attention due to a variety of potential applications. However, the practical utility of these nanocrystals has been hindered by their poor air stability, which induces undesired changes in the optical and ...
Abelson, Alex, Bustillo, Karen C, Guo, Xuyun, Law, Matt, Liao, Hong-Gang, Peng, Xinxing, Qian, Caroline, Shangguan, Junyi, Sun, Shi-Gang, Wang, Yu, Yin, Zu-Wei, Yu, Lei, Zhang, Qiubo, Zheng, Haimei, Zheng, Wenjing   +14 more
core   +11 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source