Results 101 to 110 of about 1,171,988 (336)

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

Koncepcja krzemieniarstwa schyłkowego na przykładzie eneolitu Moraw

Przegląd Archeologiczny, 2012
The concept of Terminal Lithic Industries has been developed as a result of a century-long interest of Polish archaeologists in chipped stone materials from the turn of Stone and Bronze Ages.
Jerzy Kopacz
doaj  

Towards an understanding of Early Neolithic populations: a flint perspective from Bulgaria

Documenta Praehistorica, 2008
The evidence from the Bulgarian Early Neolithic chipped stone industry reveals coherent and diagnostic flint assemblages for the vast Karanovo I and II cultural area, characterized by high quality yellow-honey coloured flint, quite long and regular ...
Maria Gurova
doaj   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

The M. S. Roberts Site (41HE8): Archaeological Investigations at a Caddo Mound Site in the Upper Neches River Basin in East Texas [PDF]

, 2017
The first archaeological investigations at the M. S. Roberts site in the Caddo Creek valley of the upper Neches River basin in East Texas (Figure 1) was by University of Texas (UT) archaeologists in 1931 (Perttula 2016).
Nelson, Bo, Perttula, Timothy K., Walters, Mark   +2 more
core   +1 more source

Millimeter‐Scale Dual‐Opposing RNA‐Gradient Hydrogel for Interfacial Gene Silencing

Advanced Science, EarlyView.
A branched microfluidic platform enables the fabrication of millimeter‐scale hydrogels with dual‐opposing RNA‐gradients for precise spatial control of cell gene expression. This device allows for the generation of multiple constructs at once, offering potential for future engineering of complex tissue interfaces with improved physiological relevance ...
Tyler Hoffman, Cong Truc Huynh, Marcus J. Goudie, Peyton J. Tebon, Hyojin Ko, Minh Khanh Nguyen, Kaelyn L. Gasvoda, Yang Song, Kirsten Fetah, Ali Khademhosseini, Song Li, Eben Alsberg   +11 more
wiley   +1 more source

Chipped stone tools of the Aboriginal tribes east and north-east of Lake Eyre, South Australia

Papers and Proceedings of the Royal Society of Tasmania
Many of the stones used for weaponry or as tools, were easy to source and therefore, any that were worn out were discarded as the supply for new ones was plentiful.
G. Aiston
semanticscholar   +1 more source

Archaeological Survey Investigations of Private Land within the boundaries of the proposed Lower Bois d’Arc Creek Reservoir Project, Fannin County, Texas [PDF]

, 2016
At the request of a private landowner that has property within the boundaries of the proposed Lower Bois d’Arc Creek Reservoir in Fannin County, we completed volunteer archaeological survey investigations on a portion of this tract of private land on ...
Cheatwood, Gary W., Nelson, Rodney J., Perttula, Timothy K., Walters, Mark   +3 more
core   +1 more source

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

Advanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab, Mehdi Salar Amoli, Tanmay Mukherjee, Maryam Bagheri, Boeun Hwang, Linqi Jin, Yamini Singh, Sophia Norton, Ashay Vishwas Bongirwar, Shweta Karnik, Lakshmi Prasad Dasi, Reza Avazmohammadi, Rene Romero, Holly D. Bauser‐Heaton, Vahid Serpooshan   +14 more
wiley   +1 more source

Stone Finds of the Starčevo Culture From the Site of Galovo in Slavonski Brod - The Results of the Lithic Analysis From Pit House SU 291 [PDF]

, 2009
Tijekom desetogodišnjih istraživanja naselja starčevačke kulture na položaju Galovo u Slavonskom Brodu, prikupljena je velika količina kamenih nalaza koji, uz keramičke nalaze, čine najbrojniji pokretni inventar.
Maja Bunčić
core   +2 more sources