Results 91 to 100 of about 802,912 (335)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Convergence of the Abelian sandpile

, 2012
The Abelian sandpile growth model is a diffusion process for configurations of chips placed on vertices of the integer lattice $\mathbb{Z}^d$, in which sites with at least 2d chips {\em topple}, distributing 1 chip to each of their neighbors in the ...
Pegden, Wesley, Smart, Charles K.
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Atom Chips: Fabrication and Thermal Properties

, 2004
Neutral atoms can be trapped and manipulated with surface mounted microscopic current carrying and charged structures. We present a lithographic fabrication process for such atom chips based on evaporated metal films.
Bar-Joseph, I., Fernholz, T., Folman, R., Groth, S., Krüger, P., Mahalu, D., Schmiedmayer, J., Wildermuth, S.   +7 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Breaking the mold: 3D cell cultures reshaping the future of cancer research

Frontiers in Cell and Developmental Biology
Despite extensive efforts to unravel tumor behavior and develop anticancer therapies, most treatments fail when advanced to clinical trials. The main challenge in cancer research has been the absence of predictive cancer models, accurately mimicking the ...
Sandra Cordeiro, Sandra Cordeiro, Beatriz B. Oliveira, Beatriz B. Oliveira, Ruben Valente, Ruben Valente, Daniela Ferreira, Daniela Ferreira, André Luz, André Luz, Pedro V. Baptista, Pedro V. Baptista, Alexandra R. Fernandes, Alexandra R. Fernandes   +13 more
doaj   +1 more source

Atom chips on direct bonded copper substrates

, 2010
We present the use of direct bonded copper (DBC) for the straightforward fabrication of high power atom chips. Atom chips using DBC have several benefits: excellent copper/substrate adhesion, high purity, thick (> 100 microns) copper layers, high ...
Burgess J. F., Evan J. Carlson, James A. Stickney, Karnakis D., Matthew B. Squires, Paul M. Baker, Sandra Wentzell, Steven M. Miller, Walter R. Buchwald   +8 more
core   +1 more source

Decision letter: Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

, 2021
Milica Radisic
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Corn Chips: Value Change Hasil Pertanian Jagung Desa Tengger Kecamatan Sale Kabupaten Rembang

E-Dimas
Kegiatan pengabdian kepada masyarakat ini ditujukan untuk pemberdayaan masyarakat Desa Tengger, Kecamatan Sale, Kabupaten Rembang. Kegiatan dilaksanakan dalam bentuk pelatihan dan pendampingan pengolahan hasil panen jagung berupa produk corn chips ...
Intan Aulia Rakhmawati
doaj   +1 more source