Results 11 to 20 of about 667,612 (106)

Human organs-on-chips for disease modelling, drug development and personalized medicine

Nature reviews genetics, 2022
The failure of animal models to predict therapeutic responses in humans is a major problem that also brings into question their use for basic research.
D. Ingber
semanticscholar   +1 more source

Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives

Microfluidics and Nanofluidics, 2021
Microfluidic chip technology is an emerging tool in the field of biomedical application. Microfluidic chip includes a set of groves or microchannels that are engraved on different materials (glass, silicon, or polymers such as polydimethylsiloxane or ...
Prapti Pattanayak, S. Singh, M. Gulati, Sukriti Vishwas, B. Kapoor, D. Chellappan, K. Anand, G. Gupta, N. Jha, P. K. Gupta, P. Prasher, K. Dua, H. Dureja, Deepak Kumar, Vijay Kumar   +14 more
semanticscholar   +1 more source

A robotic platform for fluidically-linked human body-on-chips experimentation

Nature Biomedical Engineering, 2020
Organ chips can recapitulate organ-level (patho)physiology, yet pharmacokinetic and pharmacodynamic analyses require multi-organ systems linked by vascular perfusion.
R. Novák, Miles Ingram, Susan Marquez, Debarun Das, A. Delahanty, A. Herland, Ben M. Maoz, Sauveur S. F. Jeanty, Mahadevabharath R. Somayaji, M. Burt, E. Calamari, Angeliki Chalkiadaki, Alexander Cho, Youngjae Choe, D. B. Chou, Michael J. Cronce, S. Dauth, Toni Divic, Jose Fernandez-Alcon, Thomas C. Ferrante, John P Ferrier, Edward A. FitzGerald, Rachel C. Fleming, Sasan Jalili-Firoozinezhad, Thomas Grevesse, Josue A. Goss, Tiama Hamkins-Indik, Olivier Y. F. Henry, Christopher D. Hinojosa, Tessa Huffstater, Kyung-Jin Jang, V. Kujala, L. Leng, R. Mannix, Yuka Milton, J. Nawroth, Bret A. Nestor, Carlos F. Ng, Blakely B. O’Connor, Tae-Eun Park, Henry Sanchez, Josiah Sliz, Alexandra Sontheimer-Phelps, Ben Swenor, Guy Thompson, George Touloumes, Z. Tranchemontagne, Norman Wen, Moran Yadid, A. Bahinski, G. Hamilton, D. Levner, O. Levy, A. Przekwas, R. Prantil-Baun, K. Parker, D. Ingber   +56 more
semanticscholar   +1 more source

Chips: A New Open Access Journal in the Domain of ICs

Chips, 2022
As Editor-in-Chief, it is my honor and pleasure to introduce Chips [...]
Gaetano Palumbo
semanticscholar   +1 more source

Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications.

Cell Stem Cell, 2019
The blood-brain barrier (BBB) tightly regulates the entry of solutes from blood into the brain and is disrupted in several neurological diseases. Using Organ-Chip technology, we created an entirely human BBB-Chip with induced pluripotent stem cell (iPSC)-
G. Vatine, R. Barrile, Michael J. Workman, S. Sances, Bianca K. Barriga, Matthew Rahnama, Sonalee Barthakur, Magdalena Kasendra, C. Lucchesi, Jordan Kerns, Norman Wen, Weston R. Spivia, Zhaohui Chen, J. V. Van Eyk, C. Svendsen   +14 more
semanticscholar   +1 more source

Coupling strategies for silicon photonics integrated chips [Invited]

Photonics Research, 2019
Over the last 20 years, silicon photonics has revolutionized the field of integrated optics, providing a novel and powerful platform to build mass-producible optical circuits.
R. Marchetti, C. Lacava, L. Carroll, K. Gradkowski, P. Minzioni   +4 more
semanticscholar   +1 more source

Publisher’s Note: Chips—A New Open Access Journal on Integrated Circuit

Chips, 2021
A chip is a set of electronic circuits on one small flat piece (or “chip”) of semiconductor material [...]
Rui Zuo, Zhilei Wang, Liliane Auwerter
semanticscholar   +1 more source

Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips

Scientific Reports, 2016
Three-dimensional models of kidney tissue that recapitulate human responses are needed for drug screening, disease modeling, and, ultimately, kidney organ engineering.
K. Homan, David Kolesky, Mark A. Skylar-Scott, J. Herrmann, Humphrey Obuobi, A. Moisan, J. Lewis   +6 more
semanticscholar   +1 more source

Acceleration of automatic speech recognition for low-power devices [PDF]

, 2022
(English) In this thesis, we study the challenges preventing ASR deployment on edge devices and propose innovations to tackle them, hopefully moving the technology a step forward to the future.
Pinto Rivero, Dennis
core   +1 more source

Thermal Analysis and Evaluation of Memristor-Based Compute-in-Memory Chips

Chips
The rapid advancement of artificial intelligence (AI) technologies has significantly increased the demand for high-performance computational hardware. Memristor-based compute-in-memory (CIM) technology, also known as resistive random-access memory (RRAM)-
Awang Ma, B. Gao, P. Yao, Jianshi Tang, H. Qian, Huaqiang Wu   +5 more
semanticscholar   +1 more source