Chromatographic properties of the hemolysin from the cnidarian Chironex fleckeri
Toxicon, 1969Abstract : Extracts of tentacles from the jellyfish Chironex fleckeri which possessed strong hemolytic properties were examined by ion exchange chromatography on carboxymethyl and diethylaminoethyl cellulose and by exclusion chromatography on Sephadex G-75 and G-200. In some experiments the hemolytic activity was related quantitatively to the lethality
H D, Crone, T E, Keen
openaire +2 more sources
Isolation of Different Types of Nematocyst From the Cubomedusan Chironex fleckeri
Toxicon, 1975R Endean
exaly +5 more sources
The structure and function of the nematocysts of Chironex fleckeri Southcott, 1956
Cell and Tissue Research, 1983Microbasic p-mastigophores, euryteles of two size groups, holotrichous isorhizas and atrichous isorhizas, comprise the cnidom of Chironex fleckeri, a cubozoan that has been responsible for several human fatalities. In its undischarged state each microbasic mastigophore of C.
Rifkin J., Endean R.
openaire +4 more sources
Actions of Chironex fleckeri toxins on cardiac transmembrane potentials
Toxicon, 1974Abstract Two high molecular weight proteins obtained from the tentacles of the box jellyfish, Chironex fleckeri , have toxic effects on the heart. Transmembrane potentials in atrial tissue were recorded in the presence of these toxins. Their effects on a number of parameters of the action potential have been determined from the usual voltage-time ...
openaire +3 more sources
Clinical implications of research on the box-jellyfish Chironex fleckeri
Toxicon, 1994Despite several decades of laboratory research, many anecdotal clinical publications and successful production of antivenom, the active components of Chironex fleckeri venom and their mechanisms of toxicity remain poorly elucidated. Conflicting results of animal experiments and venom studies and the lack of controlled clinical trials necessitate ...
openaire +2 more sources
Techniques applicable for purifying Chironex fleckeri (box-jellyfish) venom
Toxicon, 1990A survey of several techniques to isolate a purified lethal factor from the tentacles of Chironex fleckeri was completed. Heterologous band patterns were obtained from specific eluates after gel filtration, ion exchange, immunoaffinity and hydrophobic chromatography. SDS-PAGE revealed a dense band at 24,000 mol.
I, Othman, J W, Burnett
openaire +2 more sources
Dermatonecrotic properties of extracts from the tentacles of the cnidarian Chironex fleckeri
Toxicon, 1969Abstract : Whole extracts of the tentacles of Chironex fleckeri, active fractions obtained by Sephadex chromatography, and the toxin from nematocysts were examined for dermatonecrotic activity in rats and guinea pigs. The necrosis of skin appears to be the direct effect of the active material on the cells of the epidermis and dermis.
T E, Keen, H D, Crone
openaire +2 more sources
The hemolytic properties of extracts of tentacles from the cnidarian Chironex fleckeri
Toxicon, 1969Abstract The properties of an extract of the tentacles from Chironex fleckeri were examined to determine the nature of the hemolysin. The hemolysin was labile at room temperatures but when care was taken to prevent deterioration it had a high degree of activity which was unaffected by cholesterol.
T E, Keen, H D, Crone
openaire +2 more sources
Interaction of the hemolysin of Chironex fleckeri tentacle extracts with lipid monolayers
Toxicon, 1973Abstract An examination was made of the penetration of the hemolytic fraction of tentacle extracts of Chironex fleckeri into monolayers of lipid. The resulting increase in surface pressure was influenced by the chemical structure of the lipid; the increase occurring in the following order: cerebrosides > cephalin > sphingomyelin > gangliosides ...
openaire +3 more sources
Chironex fleckeri (Box Jellyfish) Envenomation: A Case Study
Australasian Emergency Nursing Journal, 2006Summary A 35-year-old male presented on the beach, having been stung on the leg by a box jellyfish, whilst swimming at Mission Beach, Qld. Appropriate diagnosis, the use of vinegar and pressure immobilisation bandaging and immediate pain relief helped to provide a positive outcome for this patient.
exaly +2 more sources

