Results 21 to 30 of about 94,264 (216)

Uncovering the Genetic Basis of Congenital Heart Disease: Recent Advancements and Implications for Clinical Management

CJC Pediatric &Congenital Heart Disease, Volume 2, Issue 6PB, Page 464-480, December 2023., 2023
Abstract Congenital heart disease (CHD) is the most prevalent hereditary disorder, affecting approximately 1% of all live births. A reduction in morbidity and mortality has been achieved with advancements in surgical intervention, yet challenges in managing complications, extracardiac abnormalities, and comorbidities still exist.
Karanjot Chhatwal, Jacob J. Smith, Harroop Bola, Abeer Zahid, Ashwin Venkatakrishnan, Thomas Brand   +5 more
wiley   +1 more source

Successful heart transplant in a child with congenital core myopathy and delayed‐onset restrictive cardiomyopathy due to recessive mutations in the titin (TTN) gene

Pediatric Transplantation, Volume 27, Issue 6, September 2023., 2023
Abstract Background Mutations in the TTN gene, encoding the muscle filament titin, are a major cause of inherited dilated cardiomyopathy. Early‐onset skeletal muscle disorders due to recessive TTN mutations have recently been described, sometimes associated with cardiomyopathies.
Julie Wacker, Stefano Di Bernardo, Johannes Alexander Lobrinus, Heinz Jungbluth, Mathias Gautel, Maurice Beghetti, Joel Fluss   +6 more
wiley   +1 more source

Pediatric Population Pharmacokinetic Modeling and Exposure–Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data

The Journal of Clinical Pharmacology, Volume 63, Issue 5, Page 593-603, May 2023., 2023
Abstract This study aimed to develop a population pharmacokinetic (PK) model of ambrisentan in pediatric patients (8 to <18 years) with pulmonary arterial hypertension (PAH) and compare pediatric ambrisentan systemic exposure with previously reported adult data.
Malek Okour, Mita M. Thapar, Colm Farrell, Mary Ann Lukas, Maurice Beghetti, Misba Beerahee   +5 more
wiley   +1 more source

Sequencing and titrating approach of therapy in heart failure with reduced ejection fraction following the 2021 European Society of Cardiology guidelines: an international cardiology survey

European Journal of Heart Failure, Volume 25, Issue 2, Page 213-222, February 2023., 2023
The latest European guidelines for heart failure with reduced ejection fraction (HFrEF) patients recommend initiating four major therapeutic classes rather than the sequential initiation from the previous guidelines. Without any evidence from randomized controlled trials, the perception and the practical approach to these guidelines by practicing ...
Charles Fauvel, Guillaume Bonnet, Wilfried Mullens, Clara Ines Saldarriaga Giraldo, Anja Zupan Mežnar, Anders Barasa, Mariya Tokmakova, Anastasia Shchendrygina, Francisco Moscoso Costa, Massimo Mapelli, Filip Zemrak, Laurens F. Tops, Nina Jakus, Arian Sultan, Fadel Bahouth, Chahr‐eddine Hadjseyd, Muriel Salvat, Matteo Anselmino, Daniel Messroghli, Vanessa Weberndörfer, Ilya Giverts, Thomas Bochaton, Pierre Yves Courand, Emmanuelle Berthelot, Damien Legallois, Florence Beauvais, Fabrice Bauer, Nicolas Lamblin, Thibaud Damy, Nicolas Girerd, Laurent Sebbag, Théo Pezel, Alain Cohen‐Solal, Giuseppe Rosano, François Roubille, Nathan Mewton   +35 more
wiley   +1 more source

Left atrial unloading with an 8 mm septal cutting balloon to treat postcapillary pulmonary hypertension: a case report

ESC Heart Failure, 2022
We report the case of a 58‐year‐old female with severe postcapillary pulmonary hypertension (averaged mean pulmonary arterial pressure was 49 mmHg, pulmonary arterial wedge pressure 29 mmHg, and right atrial pressure 8 mmHg) due to heart failure with ...
Fabrice Bauer, Emmanuel Besnier, Chadi Aludaat, Romain Breil, Nicolas Bettinger, Charles Fauvel, Véronique Wurtz, Olivier Raitiere, Nassima Si Belkacem, Najime Bouhzam   +9 more
doaj   +1 more source

Caring for the Aging Patient With Adult Congenital Heart Disease: A Review of Cardiac and Noncardiac Comorbidities

CJC Pediatric &Congenital Heart Disease, Volume 1, Issue 6, Page 274-281, December 2022., 2022
Abstract As the demographics of congenital heart disease (CHD) have shifted, there are now more adults living with CHD than children in North America. This presents unprecedented challenges as patients with CHD acquire noncardiac comorbidities and seek care for a variety of reasons, including noncardiac surgery and emergency department (ED) visits. CHD
Michelle Keir, Meredith Borman, Robin Clegg, Jillian Colbert, Nita Guron, Lea Harper, Doug Helmerson, Jessica Patzer, Stephen Reynolds, Nanette Alvarez   +9 more
wiley   +1 more source

Micra AV leadless pacemaker implantation after transcatheter aortic valve implantation

Pacing and Clinical Electrophysiology, Volume 45, Issue 11, Page 1310-1315, November 2022., 2022
Abstract Background Transvenous pacemaker (PM) implantation is a complication in patients undergoing transcatheter aortic valve implantation (TAVI). Recently, a second generation of leadless PMs able of atrioventricular (AV) synchronous pacing has been introduced and could be an alternative when ventricular pacing is required after TAVI.
Alexis Mechulan, Sébastien Prevot, Angélique Peret, Lyassine Nait‐Saidi, Ichem Miliani, Lauriane Leong‐Feng, Elisabeth Leude‐Vaillant, Alain Vaillant, Alain Cornen, Bernard Latiere, Marie‐Paule Giacomoni, Frédéric Collet, Vincent Bechet, Ahmed Bouharaoua, Pierre Dieuzaide   +14 more
wiley   +1 more source

Transcatheter Aortic Valve Implantation: All Transfemoral? Update on Peripheral Vascular Access and Closure

Frontiers in Cardiovascular Medicine, 2021
Transfemoral access remains the most widely used peripheral vascular approach for transcatheter aortic valve implantation (TAVI). Despite technical improvement and reduction in delivery sheath diameters of all TAVI platforms, 10–20% of patients remain ...
Nils Perrin, Nils Perrin, Guillaume Bonnet, Lionel Leroux, Réda Ibrahim, Thomas Modine, Walid Ben Ali, Walid Ben Ali   +7 more
doaj   +1 more source

60 Years After the First Woman Cardiac Surgeon: We Still Need More Women in Cardiac Surgery

CJC Open, 2021
In 1960, Dr Nina Starr Braunwald became the first woman to perform open heart surgery. Sixty years later, despite the fact that women outnumbered men in American medical school in 2017, men still dominate the field of cardiac surgery.
Sophie Weiwei Gao, MD, Jessica Forcillo, MD, MSc, Amelia Claire Watkins, MD, Mara B. Antonoff, MD, Jessica G.Y. Luc, MD, Jennifer C.Y. Chung, MD, MSc, Laura Ritchie, MD, Rachel Eikelboom, MD, Subhadra Shashidharan, MD, Michiko Maruyama, MD, Richard P. Whitlock, MD, PhD, Maral Ouzounian, MD, PhD, Emilie P. Belley-Côté, MD, PhD   +12 more
doaj   +1 more source

Les facteurs prédictifs de morbimortalité chez les patients sous ballon de contre pulsion intra-aortique en chirurgie cardiaque

The Pan African Medical Journal, 2015
Le ballon de contre pulsion intra-aortique (BCPIA) est fréquemment utilisé en chirurgie cardiaque, comme moyen d'assistance circulatoire en cas de bas débit cardiaque.
Brahim Elahmadi, Youssef Motiaa, Abdedaim Elghadbane Hatim, Noureddine Atmani, Younes Moutakillah, Fouad Amal Wahid, Youssef Elbekkali, Mahdi Ait Houssa, Rachid Razine, Abdelatif Boulahya, Mohammed Drissi   +10 more
doaj   +1 more source