Results 21 to 30 of about 3,608,928 (150)

Chitin induces steroid-resistant airway inflammation and airway hyperresponsiveness in mice

Allergology International, 2021
Background: Previous reports have shown that pathogen-associated patterns (PAMPs) induce the production of interleukin (IL)-1β in macrophages. Moreover, studies using mouse models also suggest that chitin, which acts as a PAMP, induces adjuvant effects ...
Tomohito Takeshige, Norihiro Harada, Sonoko Harada, Ayako Ishimori, Yoko Katsura, Hitoshi Sasano, Yuuki Sandhu, Kei Matsuno, Fumihiko Makino, Jun Ito, Ryo Atsuta, Hisaya Akiba, Kazuhisa Takahashi   +12 more
doaj   +1 more source

Chitin amendments eliminate the negative impacts of continuous cropping obstacles on soil properties and microbial assemblage

Frontiers in Plant Science, 2022
Continuous cropping of soybean leads to soil environment deterioration and soil-borne disease exacerbation, which in turn limits the sustainability of agricultural production.
Yanli Fan, Yanli Fan, Junjie Liu, Zhuxiu Liu, Zhuxiu Liu, Xiaojing Hu, Zhenhua Yu, Yansheng Li, Xueli Chen, Lujun Li, Jian Jin, Guanghua Wang   +11 more
doaj   +1 more source

Three LysM effectors of Zymoseptoria tritici collectively disarm chitin‐triggered plant immunity [PDF]

, 2021
Chitin is a major structural component of fungal cell walls and acts as a microbe‐associated molecular pattern (MAMP) that, on recognition by a plant host, triggers the activation of immune responses.
Chen, Hongxin, Bart P. H. J. Thomma, Mesters, J. R., Rudd, Jason, Craig I. MacKenzie, Jeroen R. Mesters, Thomma, Bart, Tian, Hui, Jason J. Rudd, Van den Berg, Grardy, Hui Tian, Tian, H., Van den Berg, G. C. M., MacKenzie, Craig, Grardy C. M. van den Berg, Thomma, B. P. H. J., Mesters, Jeroen, Rudd, J. J., Luis Rodriguez‐Moreno, MacKenzie, C. I., Rodríguez-Moreno, Luis Gabriel, Chen, H., Rodriguez-Moreno, L., Hongxin Chen   +23 more
core   +1 more source

Chitin Triggers Tissue-Specific Immunity in Wheat Associated With Fusarium Head Blight

Frontiers in Plant Science, 2022
Fusarium graminearum is one of the primary causal agents of Fusarium head blight (FHB) on wheat and barley. FHB reduces grain yield and contaminates grain with various mycotoxins, including deoxynivalenol (DON).
Guixia Hao, Helene Tiley, Susan McCormick   +2 more
doaj   +1 more source

A G-type lectin receptor-like kinase in Nicotiana benthamiana enhances resistance to the fungal pathogen Sclerotinia sclerotiorum by complexing with CERK1/LYK4

Phytopathology Research, 2023
Fungal pathogens are among the main destructive microorganisms for crops and ecosystems worldwide, causing substantial agricultural and economic losses.
Lei Pi, Yifan Zhang, Jinghao Wang, Nan Wang, Zhiyuan Yin, Daolong Dou   +5 more
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Interleukin-33 and thymic stromal lymphopoietin, but not interleukin-25, are crucial for development of airway eosinophilia induced by chitin

Scientific Reports, 2021
Exposure to various antigens derived from house dust mites (HDM) is considered to be a risk factor for development of certain allergic diseases such as atopic asthma, atopic dermatitis, rhinitis and conjunctivitis.
Ken Arae, Masashi Ikutani, Kotaro Horiguchi, Sachiko Yamaguchi, Youji Okada, Hiroki Sugiyama, Keisuke Orimo, Hideaki Morita, Hajime Suto, Ko Okumura, Haruhiko Taguchi, Kenji Matsumoto, Hirohisa Saito, Katsuko Sudo, Susumu Nakae   +14 more
doaj   +1 more source

Oral Administration of Surface-Deacetylated Chitin Nanofibers and Chitosan Inhibit 5-Fluorouracil-Induced Intestinal Mucositis in Mice [PDF]

, 2017
This study investigated the prophylactic effects of orally administered surface-deacetylated chitin nanofibers (SDACNFs) and chitosan against 5-fluorouracil (5-FU)-induced intestinal mucositis, which is a common side effect of 5-FU chemotherapy.
Azuma, Kazuo, 50194410, Okamoto, Yoshiharu, 2273, Imagawa, Tomohiro, 80264654, Osaki, Tomohiro, 100001158, 2885, 100000741, 30432610, 20232605, Ito, Norihiko, 70402980, 100000469, 100000602, Ochi, Kosuke, 4721, 100000923, 4868, 100000607, 50721841, 4641, Tsuka, Takeshi, Izawa, Hironori, Morimoto, Minoru, 26766, 26765, Saimoto, Hiroyuki, 4816, Koizumi, Ryo, 100001168, Ifuku, Shinsuke, 100000597, 40431332, 10273880, 50643235, 20186977, 4897, 100000515, 100000637, 4711, 4634, 4637   +43 more
core   +2 more sources

A structural and biochemical model of processive chitin synthesis [PDF]

, 2014
Chitin synthases (CHS) produce chitin, an essential component of the fungal cell wall. The molecular mechanism of processive chitin synthesis is not understood, limiting the discovery of new inhibitors of this enzyme class.
Ferenbach, Andrew T., van Aalten, Daan M. F., Borodkin, Vladimir S., Dorfmueller, Helge Christian; id_orcid   +3 more
core   +1 more source

The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1

eLife, 2014
Chitin is a fungal microbe-associated molecular pattern recognized in Arabidopsis by a lysin motif receptor kinase (LYK), AtCERK1. Previous research suggested that AtCERK1 is the major chitin receptor and mediates chitin-induced signaling through ...
Yangrong Cao, Yan Liang, Kiwamu Tanaka, Cuong T Nguyen, Robert P Jedrzejczak, Andrzej Joachimiak, Gary Stacey   +6 more
doaj   +1 more source

Arabidopsis ubiquitin ligase PUB12 interacts with and negatively regulates Chitin Elicitor Receptor Kinase 1 (CERK1). [PDF]

PLoS ONE, 2017
In Arabidopsis, fungal chitin is recognized as a pathogen-associated molecular pattern (PAMP) by the chitin receptor complex containing the lysin-motif (LysM) receptor-like kinases CERK1 and LYK5.
Koji Yamaguchi, Hirohisa Mezaki, Masayuki Fujiwara, Yuki Hara, Tsutomu Kawasaki   +4 more
doaj   +1 more source