Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin+4 more
wiley +1 more source
Fabrication of cell-laden hydrogel microcapsules of alginate and chitin fibrils using divalent and trivalent metal ions. [PDF]
Sapkota T+3 more
europepmc +1 more source
Chitin-binding hemagglutinin associated with cell wall of Conidiobolus lamprauges.
Fumiyasu Ishikawa+2 more
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The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
Disturbances of the microbiota–gut–brain axis are evident in people with Huntington's disease (HD) and in HD animal models. Here, we provide an overview of how the trillions of microorganisms residing in the gut, their secretory products, and the microbiota–gut–brain axis may contribute to HD pathogenesis.
Millicent N. Ekwudo+2 more
wiley +1 more source
Effects of <i>Vibrio parahaemolyticus</i> on physiology and metabolism of <i>Thalassiosira weissflogii</i> in the co-culture system. [PDF]
Wang J+5 more
europepmc +1 more source
N‐acetylglucosamine sensing in the filamentous soil fungus Trichoderma reesei
N‐acetylglucosamine (GlcNAc) is involved in diverse signaling pathways in dimorphic yeasts and bacteria, including virulence and cell death. Here, we investigated GlcNAc sensing in Trichoderma reesei. GlcNAc signaling influences around 2100 genes in this filamentous soil fungus.
Sadia Fida Ullah+6 more
wiley +1 more source
Process optimisation for improved chitinase production from marine isolate Bacillus haynesii and bioethanol production with Saccharomyces cerevisiae. [PDF]
Govindaraj V+4 more
europepmc +1 more source
The Physiological and Biochemical Studies on Insect Cuticle Formation and Chitin Synthesis
Takashi Mitsui
openalex +2 more sources
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika+7 more
wiley +1 more source
Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing. [PDF]
Chang TH+18 more
europepmc +1 more source