Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]
, 2020 Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R +3 more
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Antimicrobial Activity of Native Chitosan, Degraded Chitosan, and O-Carboxymethylated Chitosan
Journal of Food Protection, 2003 The antimicrobial activity of native chitosan was compared to that of lipase-degraded chitosan. The effects of O-carboxymethylated (O-CM) substitution on native (molecular weight, 120; degree of deacetylation, 84.71%) and lipase-degraded chitosans were also investigated.
Kyung W, Kim +3 more
openaire +2 more sources
Gold nanoparticles with chitosan, N-acylated chitosan, and chitosan oligosaccharide as DNA carriers [PDF]
Nanoscale Research Letters, 2019 Currently, gold nanoparticles have found applications in engineering and medical sciences, taking advantage from their properties and characteristics. Surface plasmon resonance, for instance, is one of the main features for optical applications and other physical properties, like high density, that represents the key for cellular uptake.
Paulina Abrica-González +6 more
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Development Of Ecologically Safe Technology Of Waste Mycelia Recycling [PDF]
, 2017 Chitosan is a cationic polymer derived by deacetylation of chitin obtained from crustaceans. Biodegradable and mucoadhesion properties of chitosan have recently led to increasing the interest.
Yegorova, O. (Oksana)
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pH-Sensitive Chitosan–Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells [PDF]
, 2019 Chitosan has been extensively studied as a genetic drug delivery platform. However, its efficiency is limited by the strength of DNA and RNA binding.
Korzhikov-Vlakh, Viktor +7 more
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Combining hyaluronic acid with chitosan enhances gene delivery [PDF]
, 2014 The low gene transfer efficiency of chitosan-DNA polyplexes is a consequence of their high stability and consequent slow DNA release. The incorporation of an anionic polymer is believed to loosen chitosan interactions with DNA and thus promote higher ...
Bitoque, Diogo +2 more
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Prawn Shell Chitosan Has Anti-Obesogenic Properties, Influencing Both Nutrient Digestibility and Microbial Populations in a Pig Model [PDF]
, 2015 This study was supported financially (Grant-Aid Agreement No. MFFRI/07/01) under the Sea Change Strategy with the support of the Marine Institute and the Department of Agriculture, Food and the Marine, funded under the National Development Plan 2007 ...
Egan, Aine M. +3 more
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Use of response surface methodology (RSM) to optimize pea starch-chitosan novel edible film formulation [PDF]
, 2017 The aim of this study was to develop an optimal formulation for preparation of an edible film from chitosan, pea starch and glycerol using response surface methodology (RSM).
Bowyer, Michael +7 more
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Synthesizing efficacious genistein in conjugation with superparamagnetic Fe3O4 decorated with bio-compatible carboxymethylated chitosan against acute leukemia lymphoma [PDF]
, 2020 Background Genistein (C15H10O5) is a soy isoflavone with anti-cancer properties such as inhibition of cell growth, proliferation and tumor invasion, but effective dosage against hematopoietic malignant cells was not in non-toxic range.
Ghasemi Goorbandi, Rachel +2 more
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Microwave-enhanced synthesis of biodegradable multifunctional chitosan hydrogels for wastewater treatment [PDF]
, 2017 Chitosan, a derivative of chitin, is a biodegradable polymer known of its favorable properties, applicable in medicine and industry. Commonly obtained chitosan hydrogels are of various swelling capacity, and may bind only anions losing their ...
Janus, Łukasz +3 more
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