Results 151 to 160 of about 394,350 (343)
Advanced Healthcare Materials, EarlyView.This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah +9 more
wiley +1 more source
Journal of Materials Research and Technology, 2020 Over the last decade, chitosan films have promising applications due to their biocompatible, biodegradable, non-toxic, and mucoadhesive nature; haemostatic effects; as well as antimicrobial and biological activities.
Noha G. Madian, Noha Mohamed
doaj
Entwicklung von reagenzfrei kovalentes Quervernetzen der chitosan-gelatine Grundgerüste Development of reagent-free covalent crosslinking of chitosan-gelatin scaffolds [PDF]
, 2008 Please refer to the attached document.
Taralp, Alpay, Zakhariouta, Anastassia
core
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun +9 more
wiley +1 more source
Carbohydrate Polymer Technologies and ApplicationsFunctionalization of chitosan as salicylaldehyde and 2-acetylphenol-based chitosan thiosemicarbazone involving amino group at C2 position of pyranose ring was confirmed by comprehensive characterization by spectroscopic and analytical ways.
Hari Sharan Adhikari +3 more
doaj
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
Advanced Healthcare Materials, EarlyView.This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source
Printed, Flexible Lactate Sensors: Design Considerations Before Performing On-Body Measurements. [PDF]
, 2019 This work reports the process of sensor development, optimization, and characterization before the transition to on-body measurements can be made. Sensors using lactate oxidase as a sensing mechanism and tetrathiafulvalene as a mediator were optimized ...
Arias, Ana Claudia +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.A decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Olawale Alimi Alimi +10 more
wiley +1 more source