Results 11 to 20 of about 65,504 (254)

Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action

open access: goldInternational Journal of Biomaterials, 2018
Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups can give derivatives of enhanced solubility and remarkable anticancer activity. The general mechanism of such activity is associated with the disturbances in normal functioning of cell cycle, interference to the central dogma of biological system from DNA to RNA ...
Hari Sharan Adhikari, Paras Nath Yadav
openalex   +3 more sources

The Microstructure, Antibacterial and Antitumor Activities of Chitosan Oligosaccharides and Derivatives

open access: yesMarine Drugs, 2022
Chitosan obtained from abundant marine resources has been proven to have a variety of biological activities. However, due to its poor water solubility, chitosan application is limited, and the degradation products of chitosan oligosaccharides are better ...
Dawei Yu   +9 more
doaj   +1 more source

Grafting of 18β-Glycyrrhetinic Acid and Sialic Acid onto Chitosan to Produce a New Amphipathic Chitosan Derivative: Synthesis, Characterization, and Cytotoxicity

open access: yesMolecules, 2021
Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water.
Wei-Yan Quan   +6 more
doaj   +1 more source

Acute and subacute in vivo safety assessment of developed chitosan derivatives for food applications

open access: yesFood Hydrocolloids for Health, 2023
The acute and subacute studies of two chitosan derivatives was conducted by oral administration on Swiss albino mice. Chitosan soluble derivatives were prepared by depolymerization method using potassium persulfate.
T.P. Punarvasu, K.V. Harish Prashanth
doaj   +1 more source

Synthesis, characterization and anticoagulant activity of chitosan derivatives

open access: yesSaudi Pharmaceutical Journal, 2020
Chitosan derivatives are reported as anticoagulants in the literature. This work was undertaken to develop novel chitosan derivatives as anticoagulants.
Mohd. Imran   +3 more
doaj   +1 more source

Mechanism and Application of Chitosan and Its Derivatives in Promoting Permeation in Transdermal Drug Delivery Systems: A Review

open access: yesPharmaceuticals, 2022
The mechanisms and applications of chitosan and its derivatives in transdermal drug delivery to promote drug permeation were reviewed in this paper.
Jinqian Ma, Yuchen Wang, Rong Lu
doaj   +1 more source

Concepts for Developing Physical Gels of Chitosan and of Chitosan Derivatives [PDF]

open access: yesGels, 2018
Chitosan macro- and micro/nano-gels have gained increasing attention in recent years, especially in the biomedical field, given the well-documented low toxicity, degradability, and non-immunogenicity of this unique biopolymer. In this review we aim at recapitulating the recent gelling concepts for developing chitosan-based physical gels.
Sacco, Pasquale   +5 more
openaire   +4 more sources

Progress in Research of Chitosan Chemical Modification Technologies and Their Applications

open access: yesMarine Drugs, 2022
Chitosan, which is derived from chitin, is the only known natural alkaline cationic polymer. Chitosan is a biological material that can significantly improve the living standard of the country.
Qizhou Chen   +7 more
doaj   +1 more source

Synthesis and Characterization of N,N,N-trimethyl-O-(ureidopyridinium)acetyl Chitosan Derivatives with Antioxidant and Antifungal Activities

open access: yesMarine Drugs, 2020
Chitosan is an active biopolymer, and the combination of it with other active groups can be a valuable method to improve the potential application of the resultant derivatives in food, cosmetics, packaging materials, and other industries.
Jingjing Zhang   +4 more
doaj   +1 more source

Chitosan/Poly(2-ethyl-2-oxazoline) films with ciprofloxacin for application in vaginal drug delivery [PDF]

open access: yes, 2020
Chitosan (CHI) and chitosan/poly(2-ethyl-2-oxazoline) (CHI/POZ)-based films were prepared by casting from aqueous solutions of polymer blends with different compositions. Ciprofloxacin was used as a model drug in these formulations. The weight, thickness,
Abilova, Guzel K.   +6 more
core   +1 more source

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