Results 11 to 20 of about 105,961 (251)

Protective Effect of Vaccine Promoted Neutralizing Antibodies against the Intracellular Pathogen Chlamydia trachomatis

Frontiers in Immunology, 2017
There is an unmet need for a vaccine to control Chlamydia trachomatis (C.t.) infections. We have recently designed a multivalent heterologous immuno-repeat 1 (Hirep1) vaccine construct based on major outer membrane protein variable domain (VD) 4 regions ...
Anja Weinreich Olsen, Emma Kathrine Lorenzen, Ida Rosenkrands, Frank Follmann, Peter Andersen   +4 more
doaj   +1 more source

Timing of progression from Chlamydia trachomatis infection to pelvic inflammatory disease: a mathematical modelling study. [PDF]

, 2012
BACKGROUND: Pelvic inflammatory disease (PID) results from the ascending spread of microorganisms from the vagina and endocervix to the upper genital tract. PID can lead to infertility, ectopic pregnancy and chronic pelvic pain. The timing of development
Herzog, Sereina A, Janneke CM Heijne, Pippa Oakeshott, Kerry Sally, Sereina A Herzog, Oakeshott Pippa, Hay Phillip, Heijne, Janneke Cm, Heijne, JC, Kerry, S, Low Nicola, Nicola Low, Low, N, Althaus, Christian L, Hay, Phillip, Christian L Althaus, Althaus, CL, Oakeshott, Pippa, Heijne Janneke CM, Herzog, SA, Oakeshott, P, Herzog Sereina A, Althaus Christian L, Kerry, Sally, Hay, P, Heijne, JCM, Low, Nicola, Phillip Hay, Sally Kerry   +28 more
core   +1 more source

Simultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract

Frontiers in Immunology, 2017
The selection of any specific immunization route is critical when defining future vaccine strategies against a genital infection like Chlamydia trachomatis (C.t.). An optimal Chlamydia vaccine needs to elicit mucosal immunity comprising both neutralizing
Jeanette Erbo Wern, Maria Rathmann Sorensen, Anja Weinreich Olsen, Peter Andersen, Frank Follmann   +4 more
doaj   +1 more source

Processing of chlamydia abortus polymorphic membrane protein 18D during the chlamydial developmental cycle [PDF]

, 2012
<p>Background: Chlamydia possess a unique family of autotransporter proteins known as the Polymorphic membrane proteins (Pmps). While the total number of pmp genes varies between Chlamydia species, all encode a single pmpD gene.
Smith, David George Emslie, Michelle Sait (122019), Longbottom, D., David G E Smith, David G. E. Smith, Aitchison, Kevin, Neil F. Inglis (122039), Wheelhouse, NM, Sait, M, Longbottom, D, Livingstone, M., Nick M. Wheelhouse (122015), McLean, K., McLean, Kevin, Wright, F., Morag Livingstone, Aitchison, K., Frank Wright (122030), Wright, F, Michelle Sait, Neil F. Inglis, Kevin McLean (122035), Wright, Frank, Livingstone, Morag, Smith, David G E, Wheelhouse, Nick M, Smith, DGE, Wheelhouse, N.M., Nick M Wheelhouse, Morag Livingstone (122027), Inglis, N.F., David Longbottom, Longbottom, David, Neil F Inglis, Wheelhouse, Nick M., Inglis, Neil F, David Longbottom (122043), Kevin Aitchison (122024), Livingstone, M, Aitchison, K, Inglis, NF, Frank Wright, Sait, M., Kevin McLean, Nick M. Wheelhouse, David G. E. Smith (122041), Sait, Michelle, Inglis, Neil F., Kevin Aitchison, McLean, K, Smith, D.G.E.   +50 more
core   +1 more source

Acceptability and satisfaction towards self‐collection for chlamydia and gonorrhoea testing among transgender women in Tangerine Clinic, Thailand: shifting towards the new normal

Journal of the International AIDS Society, 2021
Introduction Provider‐collected swabs are an unappealing procedure for many transgender women and may have led to suboptimal rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing.
Akarin Hiransuthikul, Rena Janamnuaysook, Linrada Himma, Chiraporn Taya, Tidarat Amatsombat, Phongdanai Chumnanwet, Kritima Samitpol, Artsanee Chancham, Jiratchaya Kongkapan, Jeeranuch Rueannak, Pintusorn Getwongsa, Peevara Srimanus, Nipat Teeratakulpisarn, Narukjaporn Thammajaruk, Matthew Avery, Tanyaporn Wansom, Stephen Mills, Reshmie A. Ramautarsing, Nittaya Phanuphak   +18 more
doaj   +1 more source

Frequency and risk factors for incident and redetected Chlamydia trachomatis infection in sexually active, young, multi-ethnic women: a community based cohort study. [PDF]

, 2014
OBJECTIVE: To investigate the frequency and risk factors for incident and redetected Chlamydia trachomatis infection in sexually active, young, multi-ethnic women in the community. DESIGN: Cohort study.
Jensen, JS, Reid, Fiona; id_orcid, Kerry, Sheila, Jensen, Jorgen S, Reid, F, Mallinson, Harry, Oakeshott, Pippa, Hay, PE, Oakeshott, P, Kerry, S, Aghaizu, A, Kerry, Sally, Kerry, Sarah, Aghaizu, Adamma, Mallinson, H, Hay, Phillip E   +15 more
core   +1 more source

Randomised controlled trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial. [PDF]

, 2010
OBJECTIVE: To determine whether screening and treating women for chlamydial infection reduces the incidence of pelvic inflammatory disease over the subsequent 12 months. DESIGN: Randomised controlled trial.
Atherton, H, Kerry, S., Taylor-Robinson, D, Oakeshott, P., Simms, Ian, Hay, Phillip, Hay, S., Oakeshott, Pippa, Simms, I., Taylor-Robinson, David, Oakeshott, P, Kerry, S, Hay, S, Aghaizu, A, Atherton, Helen, Hay, P., Kerry, Sally, Hay, P, Aghaizu, A., Aghaizu, Adamma, Taylor-Robinson, D., Hay, Sima, Simms, I   +22 more
core   +1 more source

Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells [PDF]

, 2008
Chlamydia are obligate intracellular bacteria that cause variety of human diseases. Host cells infected with Chlamydia are protected against many different apoptotic stimuli.
Manu Sharma, Christopher J Froelich, Oswald Monique, Sharma Manu, Lohmann, C., Oswald, M., Christine Lohmann, Sharma, Manu, Thomas Rudel, Froelich, C., Sharma, M., Monique Oswald, Froelich, Christopher J., Oliver Thieck, Rajalingam, Krishnaraj, Rudel Thomas, Thieck Oliver, Thieck, Oliver, Oswald, Monique, Froelich Christopher J., Rajalingam, K., Lohmann Christine, Rudel, T., Thieck, O., Rudel, Thomas, Krishnaraj Rajalingam, Rajalingam Krishnaraj, Lohmann, Christine   +27 more
core   +2 more sources

Chlamydia abortus Isolation and Identification in Aborted Ovine Fetus in Mari El Republic of Russia

Pathogens, 2022
Reproductive disorders, presumably caused by Chlamydia abortus, are common among the ovine population of the Mari El Republic, Russia. C. abortus infection was determined by serologic testing or isolation and detection of the organism by PCR and direct ...
Irina Matveeva, Nikolai Nikitin, Ekaterina Evtushenko, Karim Azimov, Alexey Zaberezhny, Olesya Bogomolova, Maria Kruglova, Vladimir Yeremets, Evgeniya Markova, Natalia Yeremets   +9 more
doaj   +1 more source

Penicillin kills chlamydia following the fusion of bacteria with Lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice [PDF]

, 2013
The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an ‘inclusion ...
Le Gall, SM, Colette Kanellopoulos-Langevin, Le Gall Sylvain M., Habbeddine, M, Sylvain M. Le Gall (108751), Habbeddine, Mohamed, Delarbre, C., Dumoux, M, Maud Dumoux (501153), Dumoux, Maud, Delarbre, C, Dumoux Maud, Christiane Delarbre, Hayward Richard D., Philippe Verbeke, Delarbre Christiane, Verbeke, Philippe, Kanellopoulos-Langevin Colette, Kanellopoulos-Langevin, C, Le Gall, Sylvain M, Habbeddine Mohamed, Philippe Verbeke (16975), Hayward, RD, Hayward, Richard D, Richard D Hayward, Christiane Delarbre (501155), Delarbre, Christiane, Le Gall, S.M., Habbeddine, M., Kanellopoulos-Langevin, C., Hayward, Richard D., Colette Kanellopoulos-Langevin (146985), Mohamed Habbeddine (501154), Ramsey, K., Richard D. Hayward (272234), Verbeke, P., Verbeke, P, Kanellopoulos-Langevin, Colette, Sylvain M Le Gall, Maud Dumoux, Mohamed Habbeddine, Verbeke Philippe   +41 more
core   +1 more source