Results 31 to 40 of about 86,073 (151)

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

VIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu, Qiaomei Guo, Han Yang, Huiqin Jiang, Chunyan He, Xueqing Wang, Yuting Fang, Yue Yin, Liwen Zhong, Zhijing Zhao, Jiatao Lou, Lin Wang   +11 more
wiley   +1 more source

Computational Modeling of the Chlamydial Developmental Cycle Reveals a Potential Role for Asymmetric Division

mSystems, 2023
Chlamydia trachomatis is an obligate intracellular bacterium that progresses through an essential multicell form developmental cycle. Infection of the host is initiated by the elementary body (EB).
Travis J. Chiarelli, Nicole A. Grieshaber, Cody Appa, Scott S. Grieshaber   +3 more
doaj   +1 more source

Epiphora: A Structured Diagnostic Approach for the Otolaryngologist

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Epiphora, or excessive tearing, has historically been predominantly managed by ophthalmologists. However, as there is substantial overlap between ophthalmic and otolaryngologic anatomy and pathology that may contribute to epiphora, patients with this symptom often present to otolaryngologists as well.
Luke M. O'Neil, Sam Kushner‐Lenhoff, Alexandra Van Brummen, Christopher Chambers, Hector Perez, Ashton E. Lehmann, Matthew M. Zhang, Aria Jafari   +7 more
wiley   +1 more source

Drivers of Host–Pathogen Community Assemblages in European Forests and Urban Green Spaces

Integrative Zoology, EarlyView.
ABSTRACT Despite advances in understanding infectious diseases, the persistence and re‐emergence of wildlife pathogens continue to raise public and veterinary health concerns. This study investigates the relationship between biodiversity and rodent‐borne diseases in Europe, focusing on habitat alterations and their impact on rodent diversity.
Vincent Sluydts, Marie Bouilloud, Maxime Galan, Hussein Alburkat, Anaïs Bordes, Vincent Bourret, Valeria Colombo, Luc DeBruyn, Lara Dutra, Jana Eccard, Jasmin Firozpoor, Romain Gallet, Maciej Grzybek, Heikki Henttonen, Jens Jacob, Andrew McManus, Tarja Sironen, Peter Stuart, Caroline Tatard, Benjamin Roche, Herwig Leirs, Nathalie Charbonnel   +21 more
wiley   +1 more source

Prevalence of genital Chlamydia trachomatis infection among patients attending a gynecological clinic in a tertiary hospital

Sahel Medical Journal, 2019
Background: Chlamydia trachomatis is the most common cause of sexually transmitted infections in the world. The organism causes silent infection in women and could remain unnoticed for a very long time. Nearly 80% of women are asymptomatic.
S Bello, K Tunau, S Nasir, M Yahaya, A Panti, M Hassan, E I Nwobodo, B A Ekele   +7 more
doaj   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Toward a Politics of (In)Fertility: Reproductive Debility in Africa

American Anthropologist, EarlyView.
ABSTRACT Sub‐Saharan Africa has some of the highest estimated rates of infertility or involuntary childlessness in the world, leading epidemiologists to refer to parts of the region as the “infertility belt.” The medicalization of infertility and the situating of assisted reproductive technologies (ARTs) as the treatment for infertility have siphoned ...
Tessa Moll
wiley   +1 more source

Systematic review of the clinical effectiveness and cost-effectiveness of rapid point-of-care tests for the detection of genital chlamydia infection in women and men

Health Technology Assessment, 2010
Objective: To assess whether or not the Chlamydia Rapid Test (CRT) could improve detection of genital chlamydia, and whether it is more effective than current practice using nucleic acid amplification tests (NAATs), in terms of the number of cases of ...
J Hislop, Z Quayyum, G Flett, C Boachie, C Fraser, G Mowatt   +5 more
doaj   +1 more source

Testing-adjusted chlamydia notification trends in New South Wales, Australia, 2000 to 2010

Western Pacific Surveillance and Response, 2014
Introduction: Between 2005 and 2010, Australian notification rates for chlamydia infection increased by 64% from 203 to 333 per 100 000 population. Interpreting this trend is difficult without examining rates and local patterns of testing.
Michelle Cretikos, Darren Mayne, Roderick Reynolds, Paula Spokes, Daniel Madeddu   +4 more
doaj   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source