Results 51 to 60 of about 77,066 (167)

Intrapartum oral azithromycin for maternal infection prophylaxis and the risk of postpartum hemorrhage: A secondary analysis of the A‐PLUS trial

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1562-1568, June 2026.
Abstract Objective A single oral dose of azithromycin (AZM) given during labor to women planning a vaginal delivery reduced maternal infections including sepsis, with a stronger effect in sub‐Saharan Africa than South Asia. Since maternal infection contributes to labor dysfunction and postpartum hemorrhage (PPH), we evaluated the effect of AZM on the ...
Larissa Sidze, Janet L. Moore, Waldemar A. Carlo, Musaku Mwenechanya, Elwyn Chomba, Jennifer J. Hemingway‐Foday, Avinash Kavi, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Richard Derman, Adrien L. Lokangaka, Antoinette K. Tshefu, Melissa S. Bauserman, Carl L. Bose, Poonam Shivkumar, Manjushri Waikar, Archana B. Patel, Patricia L. Hibberd, Paul Nyongesa, Fabian Esamai, Osayame A. Ekhaguere, Sherri L. Bucher, Saleem Jessani, Shiyam Sunder Tikmani, Sarah Saleem, Robert L. Goldenberg, Sk Masum Billah, Ruth Lennox, Rashidul Haque, William A. Petri, Lester Figueroa, Manolo Mazariegos, Nancy F. Krebs, Tracy L. Nolen, Marion Koso‐Thomas, Elizabeth M. McClure, Alan T. N. Tita, for the A‐PLUS Trial Group   +37 more
wiley   +1 more source

Grandmother's pregnancy complications and autism spectrum disorders in grandchildren, a California multigenerational cohort study

JCPP Advances, Volume 6, Issue 2, June 2026.
Abstract Background Pregnancy complications have been associated with offspring autism spectrum disorders (ASD). There has also been increasing evidence for multigenerational risk factors of ASD. Methods In a multigenerational California birth cohort of 1,740,379 mother–child pairs, we investigated pregnancy complications when the grandmother was ...
Ting Chow, Qi Meng, Jingyuan Xiao, Karl O’Sharkey, Zeyan Liew, Beate Ritz   +5 more
wiley   +1 more source

A General Framework for Designing and Evaluating Active‐Controlled Trials with Non‐Inferiority Objectives

Statistics in Medicine, Volume 45, Issue 13-14, June 2026.
ABSTRACT Active‐controlled trials with non‐inferiority objectives are often used when effective interventions are available, but new options may offer advantages or meet public health needs. In these trials, participants are randomized to an experimental intervention or an active control.
Antonio Olivas‐Martinez, Fei Gao, Holly Janes   +2 more
wiley   +1 more source

Early‐Life Nutritional Supplements, Household Environments, and Air Pollution Associated With Children's Helicobacter pylori Infection: A Chinese Multicenter Mother‐Child Study

Safety Science and Technology, Volume 1, Issue 2, June 2026.
Early‐life intake of nutritional additives, particularly during pregnancy and the early postnatal period, reduces the risk of Helicobacter pylori infection (HPI) in children by enhancing immune function and preventing gastrointestinal infections through proper nutrition, supporting the “(Pre‐)Fetal origins of HPI” hypothesis through the “gut–uterine ...
Chan Lu, Yufang Shan, Yuanqi Li, Wen Deng, Yuqing Chen, Yao Chen   +5 more
wiley   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 3, Page 362-373, June 2026.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Exposure to Systemic Antimicrobials During Pregnancy and Risk of Miscarriage: A Population‐Based Registry Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 7, Page 1394-1404, June 2026.
ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill, Marleen M. H. J. van Gelder, Hilde M. Engjom, Hedvig M. E. Nordeng   +3 more
wiley   +1 more source

Effects of vaginal microbiota transfer on social–emotional and neurodevelopment in cesarean‐born infants: 12‐month follow‐up of a pilot randomized clinical trial

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 6, Page 1064-1074, June 2026.
In a pilot randomized clinical trial of cesarean‐born infants, vaginal microbiota transfer improved social–emotional development at 12 months, reducing social–emotional risk and improving key subdomains, while early neurodevelopmental benefits observed at 6 months were not sustained at 12 months. Abstract Introduction To evaluate the effects of vaginal
Chuhui Zhou, Lepeng Zhou, Hao Liu, Linghong Tang, Meng Li, Huiling Shang, Daniel Krewski, Shi Wu Wen, Yan He, Ri‐hua Xie   +9 more
wiley   +1 more source

Probiotic supplementation during pregnancy for vaginal microbiota improvement and pathogen clearance: A systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 6, Page 999-1016, June 2026.
Probiotic supplementation during pregnancy shows a modest, non‐robust increase in Group B Streptococcus decolonization, with no consistent benefit for bacterial vaginosis or vulvovaginal candidiasis. Probiotics may serve as a non‐antibiotic adjunct, but standardized regimens and ecological diagnostic frameworks are required.
Zimo Liu, Roujie Huang, Tianshu Sun, Lan Zhu   +3 more
wiley   +1 more source

Oral Health—Head and Neck Cancers: Addressing Confounding Through Negative Control and Quantitative Bias Analyses

Community Dentistry and Oral Epidemiology, Volume 54, Issue 3, Page 347-353, June 2026.
ABSTRACT Objectives While there are plausible biological explanations for the association between oral health and head and neck cancers (HNC), existing studies have yielded conflicting results. A key concern is that these associations are influenced by mediators, unmeasured risk factors, and biases. To address this, a negative control exposure was used
P. K. Elango, B. Nicolau, N. Farsi, A. V. Grant, M. C. Rousseau, S. Madathil   +5 more
wiley   +1 more source

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

Immunology, Volume 178, Issue 2, Page 209-217, June 2026.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay, Mariem Garci, Ahmed Baligh Laaribi, Nabil Mathlouthi, Imene Ouzari   +4 more
wiley   +1 more source