Microbiota diversity and differences in the respiratory tract of children with pneumonia
Pediatric Investigation, EarlyView.Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge +4 more
wiley +1 more source
Can we evaluate population screening strategies in UK general practice? A pilot randomised controlled trial comparing postal and opportunistic screening for genital chlamydial infection [PDF]
, 2005 STUDY OBJECTIVE: To assess whether opportunistic and postal screening strategies for Chlamydia trachomatis can be compared with usual care in a randomised trial in general practice DESIGN: Feasibility study for a randomised controlled trial. SETTING:
Craig, N. +7 more
core +2 more sources
Childhood Chlamydia Infections
, 2023 Chlamydia pneumoniae and Chlamydia trachomatis are significant human pathogens that affect people of all ages worldwide. Chlamydia psittaci is a cause of zoonosis, and birds are the reservoirs. All are diseases for which there is no effective vaccine. C. pneumoniae is responsible for respiratory tract infections but the majority of recent C. pneumoniae
openaire +2 more sources
Infection of Hysterectomized Mice with Chlamydia muridarum and Chlamydia trachomatis [PDF]
Infection and Immunity, 2017 ABSTRACTWe studied infection and immunity of hysterectomized mice infected withChlamydia muridarumandChlamydia trachomatisto determine if there were differences between these species in their ability to infect vaginal squamous epithelial cellsin vivoindependently of proximal upper genital tract tissues. We found thatC.
Ian N. Moore +5 more
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Particle &Particle Systems Characterization, EarlyView.This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr +5 more
wiley +1 more source
Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon. [PDF]
, 2019 Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which ...
Dean, Deborah +4 more
core +1 more source
Insights Into Effects of Natural Bioactive Components on Inflammatory Diseases in Respiratory Tract
Phytotherapy Research, EarlyView.ABSTRACT The increasing prevalence of inflammatory diseases in the respiratory tract worldwide has raised concerns, and due to its high prevalence and poor prognosis, it remains a clinical focus and research hotspot. These inflammatory diseases include airway inflammation, asthma, bacterial antigens‐induced tonsil epithelial inflammation, chronic ...
Jincan Luo +4 more
wiley +1 more source
A multi-strategy antimicrobial discovery approach reveals new ways to treat Chlamydia.
PLoS BiologyWhile the excessive use of broad-spectrum antibiotics is a major driver of the global antibiotic resistance crisis, more selective therapies remain unavailable for the majority of bacterial pathogens.
Magnus Ölander +17 more
doaj +1 more source
Better than nothing? Patient-delivered partner therapy and partner notification for chlamydia: the views of Australian general practitioners [PDF]
, 2016 BACKGROUND Genital chlamydia is the most commonly notified sexually transmissible infection (STI) in Australia and worldwide and can have serious reproductive health outcomes.
Bowden, Francis +11 more
core +1 more source
Chlamydia trachomatis genital infections. [PDF]
Sexually Transmitted Infections, 1979 The prevalence and clinical features of Chlamydia trachomatis infection were studied in men with nongonococcal urethritis (NGU), in their female sexual partners, and in other women. Of 92 patients with NGU, 36 (39%) were chlamydia-positive; although all had symptoms of urethritis, fewer than half had evident discharge.
H G Robson, F D Ghadirian
openaire +3 more sources