Results 91 to 100 of about 13,299 (212)
ElaD, a Deubiquitinating Protease Expressed by E. Coli [PDF]
Background: Ubiquitin and ubiquitin-like proteins (Ubl) are designed to modify polypeptides in eukaryotes. Covalent binding of ubiquitin or Ubls to substrate proteins can be reversed by specific hydrolases.
Catic, Andre+3 more
core +1 more source
BEAN and HABAS: Polyphyletic insertions in the DNA‐directed RNA polymerase
Abstract The β and β′ subunits of the RNA polymerase (RNAP) are large proteins with complex multi‐domain architectures that include several insertional domains. Here, we analyze the domain organizations of RNAP‐β and RNAP‐β′ using sequence, experimentally determined structures and AlphaFold structure predictions.
Claudia Alvarez‐Carreño+4 more
wiley +1 more source
Signature sequences in diverse proteins provide evidence for the late divergence of the Order Aquificales [PDF]
The Aquificales species are presently believed to be the earliest branching lineage within Bacteria. However, the branching order of this group in different phylogenetic trees is highly variable and not resolved.
Emma Griffiths, Radhey S. Gupta
core +1 more source
Dynamic interactions that govern the balance between host and pathogen determine the outcome of infection and are shaped by evolutionary pressures. Eukaryotic hosts have evolved elaborate and formidable defense mechanisms that provide the basis for ...
Gabrielle Keb, Kenneth A. Fields
doaj +1 more source
Cell wall precursors are required to organize the chlamydial division septum. [PDF]
Members of the Chlamydiales order are major bacterial pathogens that divide at mid-cell, without a sequence homologue of the FtsZ cytokinetic tubulin and without a classical peptidoglycan cell wall.
Frandi, A.+5 more
core +2 more sources
Gamma-Interferon-Induced Nitric-Oxide Production Reduces Chlamydia-Trachomatis Infectivity in McCoy Cells [PDF]
McCoy cells, murine-derived cells commonly used for propagation of chlamydiae, were found to be efficient producers of nitric oxide (NO) when primed with murine gamma interferon (IFN-gamma) and then exposed to the second signals provided by Escherichia ...
Hibbs, John B.+3 more
core
Abstract BACKGROUND Campylobacter jejuni (C. jejuni), a widely distributed global foodborne pathogen, primarily linked with contaminated chicken meat, poses a significant health risk. Reducing the abundance of this pathogen in poultry meat is challenging but essential.
Farina Khattak+5 more
wiley +1 more source
Chlamydia trachomatis’ struggle to keep its host alive
Bacteria of the phylum Chlamydiae infect a diverse range of eukaryotic host species, including vertebrate animals, invertebrates, and even protozoa. Characteristics shared by all Chlamydiae include their obligate intracellular lifestyle and a biphasic ...
Barbara S. Sixt+2 more
doaj +1 more source
Chlamydia trachomatis is a human pathogen associated with significant morbidity worldwide. As obligate intracellular parasites, chlamydiae must survive within eukaryotic cells for sufficient time to complete their developmental cycle.
Mary M. Weber+8 more
doaj +1 more source
A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis. [PDF]
UnlabelledIn a screen for compounds that inhibit infectivity of the obligate intracellular pathogen Chlamydia trachomatis, we identified the 2-pyridone amide KSK120.
Almqvist, Fredrik+12 more
core +4 more sources