Amoebal endosymbiont Parachlamydia acanthamoebae Bn9 can grow in immortal human epithelial HEp-2 cells at low temperature; an in vitro model system to study chlamydial evolution. [PDF]
PLoS ONE, 2015 Ancient chlamydiae diverged into pathogenic and environmental chlamydiae 0.7-1.4 billion years ago. However, how pathogenic chlamydiae adapted to mammalian cells that provide a stable niche at approximately 37 °C, remains unknown, although environmental ...
Chikayo Yamane +11 more
doaj +1 more source
Chlamydia species-dependent differences in the growth requirement for lysosomes.
PLoS ONE, 2011 Genome reduction is a hallmark of obligate intracellular pathogens such as Chlamydia, where adaptation to intracellular growth has resulted in the elimination of genes encoding biosynthetic enzymes.
Scot P Ouellette +4 more
doaj +1 more source
Microtubules in Bacteria: Ancient Tubulins Build a Five-Protofilament Homolog of the Eukaryotic Cytoskeleton [PDF]
, 2011 Microtubules play crucial roles in cytokinesis, transport, and motility, and are therefore superb targets for anti-cancer drugs. All tubulins evolved from a common ancestor they share with the distantly related bacterial cell division protein FtsZ, but ...
A Briegel +66 more
core +5 more sources
Protochlamydia naegleriophila as Etiologic Agent of Pneumonia
Emerging Infectious Diseases, 2008 Using ameba coculture, we grew a Naegleria endosymbiont. Phenotypic, genetic, and phylogenetic analyses supported its affiliation as Protochlamydia naegleriophila sp. nov. We then developed a specific diagnostic PCR for Protochlamydia spp.
Nicola Casson +4 more
doaj +1 more source
Animal Chlamydiae: A Concern for Human and Veterinary Medicine
Pathogens, 2022 The Chlamydiae are a phylum of obligate intracellular, Gram-negative bacteria with a biphasic lifecycle [...]
Hanna Marti, Martina Jelocnik
doaj +1 more source
Presence of Waddlia chondrophila in hot water systems from non-domestic buildings in France [PDF]
, 2018 Postprint (author's final ...
Agustí Adalid, Gemma +4 more
core +2 more sources
Detection of Chlamydial DNA from Mediterranean Loggerhead Sea Turtles in Southern Italy
Animals, 2022 Chlamydiae are obligate intracellular bacteria that include pathogens of human and veterinary importance. Several reptiles were reported to host chlamydial agents, but pathogenicity in these animals still needs clarification.
Antonino Pace +9 more
doaj +1 more source
The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling [PDF]
, 2014 Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole.
Bastidas, Robert J. +6 more
core +3 more sources
Workplace Health & Safety, 2019 Increasing rates for chlamydia and other sexually transmitted infections pose a global public health issue. Untreated chlamydia infections create an economic burden on the health care system, employers, and society. Occupational and environmental health nurses can help promote health awareness about chlamydia, teach prevention strategies, and ...
openaire +2 more sources
The Impact of Lateral Gene Transfer in Chlamydia
Frontiers in Cellular and Infection Microbiology, 2022 Lateral gene transfer (LGT) facilitates many processes in bacterial ecology and pathogenesis, especially regarding pathogen evolution and the spread of antibiotic resistance across species.
Hanna Marti +2 more
doaj +1 more source