Results 111 to 120 of about 5,109 (221)

Sustained impact of bivalent HPV immunisation on CIN incidence over two rounds of cervical screening

International Journal of Cancer, Volume 158, Issue 5, Page 1348-1360, 1 March 2026.
What's New? While vaccination against high‐risk HPV infection, the primary cause of cervical malignancy, has demonstrated long‐term effectiveness in clinical trials, real‐life longitudinal data are lacking. Here, the authors present linked long‐term screening data on the effectiveness of bivalent HPV vaccination with a minimum follow‐up of 54 months ...
Timothy J. Palmer, Kimberley Kavanagh, Kate Cuschieri, Ross L. Cameron, Catriona Graham, Allan Wilson, Kirsty Roy   +6 more
wiley   +1 more source

In vitro susceptibility of recent Chlamydia trachomatis clinical isolates to the CtHtrA inhibitor JO146 [PDF]

, 2015
© 2015 Institut Pasteur. The present study aimed to establish if a previously identified Chlamydia trachomatis HtrA (CtHtrA) inhibitor, JO146, is effective against currently circulating clinical isolates to validate if CtHtrA is a clinically relevant ...
Allan, JA, Beagley, KW, Hocking, JS, Huston, WM, Lawrence, A, Ong, VA, Tabrizi, SN, Timms, P, Vodstrcil, LA   +8 more
core   +3 more sources

Exploring the Key Role of Nanotechnology on Intratumoral Microbiome Modulation for Cancer Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source

T‐cell receptor–like chimeric antigen receptor T cells targeting mesothelin: A first‐in‐human dose‐escalation trial for platinum‐resistant advanced ovarian cancer

Cancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Ovarian cancer remains a formidable therapeutic challenge due to late diagnosis, high recurrence rates, and limited treatment options. Mesothelin (MSLN) is highly expressed in ovarian cancer, making it a promising target for immunotherapy.
Yiyang Shan, Bo Ding, Feng Ji, Hao Lin, Weiwei Shi, Enxiu Wang, Chen Wang, Yang Shen   +7 more
wiley   +1 more source

Intracellular Tryptophan Pool Sizes May Account for Differences in Gamma Interferon-Mediated Inhibition and Persistence of Chlamydial Growth in Polarized and Nonpolarized Cells [PDF]

, 1999
Colleen D. Kane, Renee M. Vena, Scot P. Ouellette, Gerald I. Byrne   +3 more
openalex   +2 more sources

Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report. [PDF]

, 2013
Background. Infectious diseases seem to be an important and independent risk factor for renal failure, but the underlying mechanism of renal involvement during some kinds of infectious diseases is still unclear, even if the literature data report ...
Falsaperla, Raffaele, Giunta, Leandra, Nunnari, Giuseppe, Pavone, Piero, Rapisarda, Venerando, Spataro, Giuseppina, Velardita, Mario, Vitaliti, Giovanna   +7 more
core   +3 more sources

Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025.
Kedi Wang, Dongjiang Xu, Yan Gao, Wen Zhao, Kaihui Ma   +4 more
wiley   +1 more source

Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ [PDF]

, 2013
Chlamydiae are important pathogens and symbionts with unique cell biological features. They lack the cell-division protein FtsZ, and the existence of peptidoglycan (PG) in their cell wall has been highly controversial.
Aistleitner, Karin, Biboy, Jacob, Brun, Yves V., Gray, Joe, Hall, Edward, Horn, Matthias, Jensen, Grant J., Kuru, Erkin, Pilhofer, Martin, VanNieuwenhze, Michael S., Vollmer, Waldemar   +10 more
core   +2 more sources

Combatting Misinformation: Adolescents' Reported Need and Desire for School‐Based Education About Crisis Pregnancy Centers

Journal of School Health, Volume 96, Issue 2, February 2026.
ABSTRACT Background Adolescents are uniquely vulnerable to Crisis Pregnancy Centers (CPCs), which advertise free reproductive health services but do not provide licensed healthcare or transparency in their practices. Despite the prevalence and harms of attending these clinics, no studies to date have characterized adolescents' baseline understanding ...
Abigail Liberty, Kimberly Schaefer, Reed Sheridan, Maria I. Rodriguez   +3 more
wiley   +1 more source