Results 91 to 100 of about 365,054 (191)

Chlamydia Exploit the Mammalian Tryptophan-Depletion Defense Strategy as a Counter-Defensive Cue to Trigger a Survival State of Persistence.

Frontiers in Cellular and Infection Microbiology, 2014
We previously proposed that in Chlamydiaceae rapid vegetative growth and a quiescent state of survival (persistence) depend upon alternative protein translational profiles dictated by host tryptophan (Trp) availability.
Carol A Bonner, Gerald I Byrne, Roy A Jensen   +2 more
doaj   +1 more source

Chlamydia Trachomatis Persistence in Vitro: An Overview

, 2010
Chlamydiae growing in target mucosal human epithelial cells in vitro can transition from their normal developmental cycle progression, alternating between infectious but metabolically inactive elementary bodies to metabolically active but noninfectious ...
Wyrick, Priscilla B.
core   +1 more source

Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon

mBio, 2019
Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which ...
Naraporn Somboonna, Noa Ziklo, Thomas E. Ferrin, Jung Hyuk Suh, Deborah Dean   +4 more
doaj   +1 more source

Differential expression of chlamydial signal transduction genes in normal and interferon gamma-induced persistent Chlamydophila pneumoniae infections

, 2006
Characteristic features of the persistent chlamydial developmental cycle, associated with chronic infections in both humans and animals, include the generation of non-replicative, morphologically aberrant bodies which are distinct from normal propagating
Hogan, R J, Timms, Peter, Polkinghorne, Adam, Polkinghorne, A, Vaughan, L, Summersgill, J T, Summersgill, James, Hogan, Richard, Vaughan, Lloyd   +8 more
core   +1 more source

The identification and characterization of novel persistence genes in chlamydia trachomatis

, 2016
Indiana University-Purdue University Indianapolis (IUPUI)Chlamydia trachomatis is an obligate intracellular bacterial pathogen that can infect the eyes, genital tract, and disseminate to lymph nodes in humans. Many C.
Muramatsu, Matthew Kazuyuki
core   +1 more source

New insights into Chlamydiae persistence: An energy metabolism strategy?

, 2013
Chlamydiaceae is a family of obligate intracellular bacteria generally considered energy parasites. Several studies have suggested that Chlamydiae are capable of independently producing energy and, more importantly, several genes involved in the energy ...
DI PIETRO, Marisa, SESSA, Rosa, DE SANTIS, FIORENZO, FILARDO, SIMONE   +3 more
core  

Chlamydiae under stress : environmental conditions influence the production and localization of chlamydial antigens

Chlamydiae are obligate intracellular pathogens that cause several serious conditions within the human host. Many of the symptoms associated with infection are thought to stem from the development of aberrant, or persistent, chlamydiae.
Brown, Wendy J.
core   +3 more sources

Chlamydia psittaci reference genes for normalisation of expression data differ depending on the culture conditions and selected time points during the chlamydial replication cycle

Journal of Veterinary Research, 2016
Introduction: Chlamydia psittaci is a gram-negative obligate intracellular pathogen of birds. Poultry infections lead to economic losses and can be transmitted to humans.
Van Lent Sarah, Vanrompay Daisy
doaj   +1 more source

Herpes Simplex Virus Glycoprotein D/Host Cell Surface Interaction Stimulates \u3cem\u3eChlamydia trachomatis\u3c/em\u3e Persistence via a Novel Pathway. [PDF]

, 2008
When presented with certain unfavorable environmental conditions, C. trachomatis reticulate bodies (RBs) enter into a viable, yet noncultivable state called persistence. Two hallmarks of persistent chlamydiae are swollen, aberrantly shaped RBs, as viewed
Vanover, Jennifer
core   +1 more source

An Early Event in the Herpes Simplex Virus Type-2 Replication Cycle Is Sufficient to Induce Chlamydia Trachomatis Persistence

, 2007
Epidemiological studies have demonstrated that co-infections of herpes simplex virus type 2 (HSV-2) and Chlamydia trachomatis occur in vivo. Data from a tissue culture model of C. trachomatis/HSV-2 co-infection indicate that viral co-infection stimulates
Sun, Jingru, Kintner, Jennifer, Vanover, Jennifer, Deka, Srilekha, Whittimore, Judy, Schoborg, Robert V.   +5 more
core   +1 more source