Persistent Chlamydial Envelope Antigens in Antibiotic‐Exposed Infected Cells Trigger Neutrophil Chemotaxis [PDF]
An in vitro coculture model system was used to explore conditions that trigger neutrophil chemotaxis to Chlamydia trachomatis infected human epithelial cells (HEC-1B). Polarized HEC-1B monolayers growing on extracellular matrix (ECM) were infected with C. trachomatis serovar E. By 36 h, coincident with the secretion of chlamydial lipopolysaccharide and
Priscilla B. Wyrick+4 more
openaire +2 more sources
Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab+4 more
wiley +1 more source
Lead discovery strategies for identification of Chlamydia pneumoniae inhibitors [PDF]
Throughout its known history, the gram-negative bacterium Chlamydia pneumoniae has remained a challenging target for antibacterial chemotherapy and drug discovery.
Hanski, Leena Lyydia, Vuorela, Pia
core +2 more sources
Tissue MicroArray (TMA) analysis of normal and persistent
Background Chlamydophila pneumoniae infection has been implicated as a potential risk factor for atherosclerosis, however the mechanism leading to persistent infection and its role in the disease process remains to be elucidated. Methods We validated the
Timms Peter+8 more
doaj +1 more source
Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao+4 more
wiley +1 more source
Mixed infection by fowlpox virus and Chlamydophila psittaci in a commercial laying hen flock [PDF]
An outbreak of fowlpox occurred in a commercial laying hen flock in one of the western provinces of Poland. Clinical signs suggested fowlpox and the diagnosis was confirmed by histopathological detection of Bollinger bodies within the epithelial cells ...
Jasik, Agnieszka+5 more
core +1 more source
For intracellular Chlamydiaceae, there is no need to withstand osmotic challenges, and a functional cell wall has not been detected in these pathogens so far. Nevertheless, penicillin inhibits cell division in Chlamydiaceae resulting in enlarged aberrant
Stefania eDe Benedetti+7 more
doaj +1 more source
Chlamydia trachomatis infection induces replication of latent HHV-6. [PDF]
Human herpesvirus-6 (HHV-6) exists in latent form either as a nuclear episome or integrated into human chromosomes in more than 90% of healthy individuals without causing clinical symptoms.
Bhupesh K Prusty+7 more
doaj +1 more source
Microbiota diversity and differences in the respiratory tract of children with pneumonia
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge+4 more
wiley +1 more source
Ironing Out the Unconventional Mechanisms of Iron Acquisition and Gene Regulation in Chlamydia
The obligate intracellular pathogen Chlamydia trachomatis, along with its close species relatives, is known to be strictly dependent upon the availability of iron.
Nick D. Pokorzynski+2 more
doaj +1 more source