A cyclophilin A inducible expressed in gonad of zhikong scallop Chlamys farreri
Molecular Biology Reports, 2008Cyclophilin A (CypA), a receptor for the immunosuppressive agent cyclosporin A (CsA), is a cis-trans peptidyl-prolyl isomerase (PPIase) which accelerates the cis-trans isomerization of prolyl-peptide bonds, interacts with a variety of proteins and therefore regulates their activities. One CypA (designated CfCypA) cDNA was cloned from Chlamys farreri by
Xiaoyan, Song +8 more
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Scallops are delicious and healthy, but their filter feeding habits make them vulnerable to ingesting and accumulating toxic chemicals from the environment, resulting in food safety issues. The purpose of this study was to investigate the effects of steaming process on the concentration, distribution and bioaccessibility of cadmium (Cd) in Chlamys ...
Fei, Xu +4 more
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Dietary accumulation of tetrabromobisphenol A and its effects on the scallop Chlamys farreri
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2015Tetrabromobisphenol A (TBBPA) is currently the most widely-used brominated flame retardant (BFR) and has been proven to have a very high toxicity to aquatic organisms including bivalves. In this study, a laboratory experiment was conducted to obtain a better understanding of the role of algae food on the bioaccumulation of TBBPA and its effects on the ...
Fengxiao, Hu +3 more
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The versatile functions of LRR-only proteins in mollusk Chlamys farreri
Developmental & Comparative Immunology, 2017Leucine-rich repeat (LRR)-only proteins are involved in the innate immune responses as they mediate protein-ligand interactions. In the present study, three novel LRR-only proteins, CfLRRop-4, CfLRRop-5 and CfLRRop-6, were identified and characterized from Zhikong scallop Chlamys farreri. They all contained LRR motifs with consensus signature sequences
Mengqiang Wang +6 more
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The mechanism of apoptosis of Chlamys farreri hemocytes under benzopyrene stress in vitro
Science of The Total Environment, 2021Hemocytes are critical to the immune defense system of bivalves, and polycyclic aromatic hydrocarbons (PAHs) can mediate the immunity of bivalves by affecting the apoptosis of hemocytes. However, the underlying mechanism is still unclear. Chlamys farreri, as an important economic bivalve, was selected as the research subject for this experimentation ...
Yimeng, Tian +5 more
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Characterization of an ETS transcription factor in the sea scallop Chlamys farreri
Developmental & Comparative Immunology, 2009We have cloned and characterized a cDNA encoding a putative ETS transcription factor, designated Cf-ets. The Cf-ets encodes a 406 amino acid protein containing a conserved ETS domain and a Pointed domain. Phylogenetic analysis revealed that Cf-ets belongs to the ESE group of ETS transcription factor family.
Hongming, Ma +4 more
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The arginine kinase in Zhikong scallop Chlamys farreri is involved in immunomodulation
Developmental & Comparative Immunology, 2012Arginine kinase (AK) catalyzes the reversible phosphorylation of l-arginine to form phosphoarginine, and plays a critical role in energy metabolism in invertebrates. In the present study, a scallop AK gene was identified from Chlamys farreri with an open reading frame (ORF) of 1101bp encoding for a protein of 366 amino acids (designed as CfAK).
Xiaowei, Shi +6 more
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Cloning and mineralization-related functions of the calponin gene in Chlamys farreri
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2016Calponin is a widely distributed protein which is associated with the bio-mineralization process in vertebrates. Recently, a new type of calponin has been found in shellfish; the present study aimed to determine if this gene in shellfish functions in bio-mineralization, one of the most important processes in a mollusk's growth. We chose Chlamys farreri,
Jun, Wang +7 more
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Acetylcholine modulates the immune response in Zhikong scallop Chlamys farreri
Fish & Shellfish Immunology, 2014Acetylcholine (ACh) is an indispensable neurotransmitter and neuromodulator in the cholinergic nervous system and it is implicated in the dynamic modulation of immune response in vertebrates. Although ACh has also been identified in most invertebrates, the knowledge about its immunomodulation is still limited.
Xiaowei, Shi +5 more
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Characterisation of monoclonal antibodies to haemocyte types of scallop (Chlamys farreri)
Fish & Shellfish Immunology, 2005Four monoclonal antibodies (MAbs) (1E7, 1F12, 2H5, 2C6) against haemocytes of scallop (Chlamys farreri) were produced by immunising Balb/C mice. Analysed by the indirect immunofluorescence assay test (IIFAT), immunocytochemical assay, flow cytometry (FCM) and Western-blotting, they showed specificity for more than one haemocyte type (hyalinocyte and ...
Xing, Jing, Zhan, Wenbin
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