Results 91 to 100 of about 23,600 (247)
New developments in the treatment of chronic lymphocytic leukemia: role of obinutuzumab
Therapeutics and Clinical Risk Management, 2015 Arpita Shah Department of Pharmacy, Georgia Regents University Medical Center, Augusta, GA, USA Abstract: Obinutuzumab is a novel glycoengineered type II anti-CD20 monoclonal antibody with a higher affinity for CD20 epitope, enhanced antibody-dependent
Shah A
doaj
Low Dose Pegylated Interferon Alpha as a First‐Line Treatment for Necrobiotic Xanthogranuloma
JEADV Clinical Practice, Volume 5, Issue 1, Page 215-218, March 2026.ABSTRACT Necrobiotic xanthogranuloma (NXG) is a rare, progressive granulomatous disorder frequently associated with monoclonal gammopathy, particularly monoclonal gammopathy of undetermined significance (MGUS). It typically presents with indurated to ulcerative yellowish plaques or nodules, often with ocular involvement.
Ishana Dixit +2 more
wiley +1 more source
International Journal of Molecular Sciences, 2018 In this study, two DNA-targeting agents, cisplatin and chlorambucil, were combined in a Pt(IV) prodrug, 1, which was thoroughly characterized by means of spectroscopic and spectrometric techniques. Tested towards a panel of various human tumor cell lines,
Diego Montagner +4 more
semanticscholar +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, Volume 36, Issue 16, 23 February 2026.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog. [PDF]
, 2019 BackgroundEvolution of indolent to aggressive lymphoma has been described in dogs but is difficult to distinguish from the de novo development of a second, clonally distinct lymphoma.
Bienzle, Dorothee +6 more
core +1 more source
Leukemia, 2017 Randomized phase 3 study of lenalidomide versus chlorambucil as first-line therapy for older patients with chronic lymphocytic leukemia (the ORIGIN trial)
A. Chanan-Khan +11 more
semanticscholar +1 more source
Drug Development and Industrial Pharmacy, 2019 A possible way of improving the activity and selectivity profile of antitumor agents is to design drug carrier systems employing soluble macromolecules.
Sonia Mendoza-Cardozo +6 more
semanticscholar +1 more source
Rituximab in combination with high-dose methylprednisolone for the treatment of chronic lymphocytic leukemia. [PDF]
, 2009 We observed that high-dose methylprednisolone (HDMP) and rituximab was well tolerated and had promising activity when used in combination to treat patients with fludarabine-refractory chronic lymphocytic leukemia (CLL).
Bole, J +6 more
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Combination of Chlorambucil and Mercaptopurine Show Effective Anti-Cancer Effects in Mice Model
International Journal of Nanomedicine, 2023 Weibing Xu,1 Yuxin Di,1 Shengjing Chu,1 Zixuan Wang,1 Haitao Long,1 Lumei Pu,1 Runtian Ma,1 Yanwei Wang2 1College of Science, Gansu Agricultural University, Lanzhou, 730000, People’s Republic of China; 2Department of Chemical and Materials Engineering ...
Xu W +7 more
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Targeted therapy and outcome in chronic lymphocytic leukemia [PDF]
, 2014 Despite major advances, chronic lymphocytic leukemia (CLL) is still considered incurable. Fludarabine refractory patients and those with TP53disruptions have a particularly poor prognosis.
Eketorp Sylvan, Sandra
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