Results 111 to 120 of about 24,793 (292)

Protein ruthenation and DNA alkylation: chlorambucil-functionalized RAPTA complexes and their anticancer activity.

Dalton Transactions, 2015
Chemotherapeutics for the treatment of tumorigenic conditions that feature novel modes of action are highly sought after to overcome the limitations of current chemotherapies.
A. Nazarov, S. Meier, Olivier Zava, Yulia N. Nosova, E. Milaeva, C. Hartinger, P. Dyson   +6 more
semanticscholar   +1 more source

The Interaction of the Chemotherapeutic Drug Chlorambucil with Human Glutathione Transferase A1-1: Kinetic and Structural Analysis [PDF]

, 2013
Glutathione transferases (GSTs) are enzymes that contribute to cellular detoxification by catalysing the nucleophilic attack of glutathione (GSH) on the electrophilic centre of a number of xenobiotic compounds, including several chemotherapeutic drugs ...
Axarli, Irine, Bethanis, Kostas, Chiniadis, Lykourgos, Clonis, Yannis D., Karpusas, Michael, Labrou, Nikolaos E., Papakyriakou, Athanasios, Scopelitou, Katholiki   +7 more
core   +3 more sources

Immunochemotherapy of Cancer with Chlorambucil-carrying Antibody [PDF]

, 1972
T. Ghose, S. T. Norvell, A. Guclu, Donald P. Cameron, A. Bodurtha, A. S. Macdonald   +5 more
openalex   +1 more source

Comparative effectiveness and tolerance of immunosuppressive treatments for idiopathic membranous nephropathy: A network meta-analysis.

PLoS ONE, 2017
BackgroundImmunosuppressive agents in general are shown to prevent renal progression and all-cause mortality in idiopathic membranous nephropathy (IMN) patients with nephrotic syndrome.
Song Ren, Ying Wang, Ying Wang, Li Xian, Tadashi Toyama, Meg Jardine, Guisen Li, Vlado Perkovic, Daqing Hong   +8 more
doaj   +1 more source

Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog. [PDF]

, 2019
BackgroundEvolution of indolent to aggressive lymphoma has been described in dogs but is difficult to distinguish from the de novo development of a second, clonally distinct lymphoma.
Bienzle, Dorothee, Darzentas, Nikos, Deravi, Nariman, Hwang, Mei-Hua, Keller, Stefan M, Matsuyama, Arata, Richardson, Danielle   +6 more
core   +1 more source

Successful long-term monotherapy with rituximab in a patient with chronic lymphocytic leukemia of the B-cell-lineage: a case report

Journal of Medical Case Reports, 2008
Introduction Treatment of chronic lymphocytic leukemia of the B-cell-lineage is strongly based upon clinical staging because of the heterogeneous clinical course of this disease.
Sturm Isrid, Oertel Joachim, Oertel Stephan, Westermann Jörg, Pezzutto Antonio   +4 more
doaj   +1 more source

Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzumab for treatment-naive chronic lymphocytic leukaemia (ELEVATE-TN): a randomised, controlled, phase 3 trial

The Lancet, 2020
J. Sharman, M. Egyed, W. Jurczak, A. Skarbnik, J. Pagel, I. Flinn, M. Kamdar, T. Munir, R. Walewska, G. Corbett, L. Fogliatto, Y. Herishanu, V. Banerji, S. Coutre, G. Follows, P. Walker, K. Karlsson, P. Ghia, A. Janssens, F. Cymbalista, J. Woyach, G. Salles, W. Wierda, R. Izumi, V. Munugalavadla, P. Patel, M. Wang, S. Wong, J. Byrd   +28 more
semanticscholar   +1 more source

Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia [PDF]

, 1977
A Sawitsky, KR Rai, O Glidewell, RT Silver   +3 more
openalex   +1 more source

Bi-weekly chlorambucil treatment of chronic lymphocytic leukemia [PDF]

, 1974
William H. Knospe, Virgil Loeb, Charles M. Huguley   +2 more
openalex   +1 more source

Drug therapy of primary biliary diseases: classical and modern strategies [PDF]

, 2013
Definition: Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are both cholestatic liver diseases. A common feature of these disorders is the accumulation of bile acids in the liver and blood, presumably because of decreased ...
Leuschner, Ulrich, Schlichting, Julia
core