Results 191 to 200 of about 10,072 (202)

Effects of Chlorambucil on human chromosomes

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1973
Abstract No significant amount of chromosomal damage was found in the 48-h cultures of lymphocytes of 18 patients who had been treated with the bifunctional alkylating agent chlorambucil (CBC). However, there was suggestive evidence of chromatid damage ( i.e. of types attributable to damage during or after DNA synthesis in the cell cycle). In marrow
Alan C. Stevenson, Chandrakant Patel
openaire   +3 more sources

Studies of chlorambucil—DNA adducts

Biochemical Pharmacology, 1992
Chlorambucil (CLB) is a bifunctional nitrogen mustard whose therapeutic and major side-effects are thought to be caused by binding to DNA. HPLC analysis of hydrolyzed DNA from L1210 cells incubated with [14C]CLB generated two peaks of radioactivity, indicating the formation of two or more major adducts.
openaire   +3 more sources

The metabolism of chlorambucil

Biochemical Pharmacology, 1976
A, McLean, D, Newell, G, Baker
openaire   +2 more sources

Chlorambucil Poisoning

Archives of Pediatrics & Adolescent Medicine, 1968
A A, Green, J L, Naiman
openaire   +2 more sources

CHLORAMBUCIL IN ERYTHRODERMIA

The Lancet, 1960
Josef Libánský, Jirí Trapl
openaire   +3 more sources

Chlorambucil and Malignancy

Ophthalmology, 2010
Frederick Oh, Ozlem Sahin, Deborah M. Little, Howard H. Tessler, Debra A. Goldstein, Andrea D. Birnbaum   +5 more
openaire   +3 more sources

Chlorambucil and Leukemia

New England Journal of Medicine, 1977
openaire   +3 more sources

Chlorambucil-induced myelofibrosis

Clinical & Laboratory Haematology, 2008
Thomas C. Pearson, E. J. Gaminara
openaire   +3 more sources

Treatment of Behcet’s Disease with Chlorambucil

Ophthalmologica, 1975
F.M. Smulders, J.A. Oosterhuis
openaire   +3 more sources

Chlorambucil

2016
openaire   +1 more source