Results 41 to 50 of about 24,793 (292)

Chlorambucil effect on B lymphocites in the peripheral blood of patients with chronic lymphocytic leukemia: Cell ultrastructure investigation [PDF]

Vojnosanitetski Pregled, 2003
B type Chronic Lymphocytic Leukemia (B-CLL) is a malignant disease characterized by the progressive accumulation of morphologically mature, but immunologically dysphunctional CD 5+ lymphocytes in the blood, bone marrow and lymphatic organs in the early ...
Brajušković Goran R., Marjanović Slobodan A., Škaro-Milić Anđelija B.   +2 more
doaj   +1 more source

Real-world clinical experience in the Connect® chronic lymphocytic leukaemia registry: a prospective cohort study of 1494 patients across 199 US centres. [PDF]

, 2016
The clinical course of chronic lymphocytic leukaemia (CLL) is heterogeneous, and treatment options vary considerably. The Connect® CLL registry is a multicentre, prospective observational cohort study that provides a real-world perspective on the ...
Farber, Charles M, Flick, E Dawn, Flinn, Ian W, Flowers, Christopher R, Grinblatt, David L, Kay, Neil E, Kipps, Thomas J, Kiselev, Pavel, Kozloff, Mark F, Lamanna, Nicole, Mato, Anthony, Nabhan, Chadi, Sharman, Jeff P, Sullivan, Kristen, Swern, Arlene S, Weiss, Mark A   +15 more
core   +1 more source

Chlorambucil vs. combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia [PDF]

Cancer, 1973
Eleven patients with chronic lymphocytic leukemia were treated with chlorambucil alone and 15 patients received combined chlorambucil-prednisone therapy in a double-blind study. Mean age, duration of disease, physical findings, and hematologic data in the two groups were essentially comparable. Complete remission was observed in 3 and partial remission
Dinesh V. Desai, Tin Han, Ediz Z. Ezdinli, Katsutaro Shimaoka   +3 more
openaire   +3 more sources

Paraneoplastic pemphigus - a rare autoimmune complication in patients with chronic lymphocytic leukemia

Онкогематология, 2022
This is a case report of the 64-year-old male patient who suffered of previously untreated chronic lymphocytic leukemia (CLL), and paraneoplastic pemphigus. He was treated with prednisolone, MabThera, chlorambucil and cyclophosphamide.
M. A. Volkova, M. Yu. Kitchigina, N. S. Potekaev, N. P. Teplyuk, A. G. Kupriyanova   +4 more
doaj   +1 more source

Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions.

New England Journal of Medicine, 2014
BACKGROUND The monoclonal anti-CD20 antibody rituximab, combined with chemotherapeutic agents, has been shown to prolong overall survival in physically fit patients with previously untreated chronic lymphocytic leukemia (CLL) but not in those with ...
V. Goede, K. Fischer, R. Busch, A. Engelke, B. Eichhorst, C. Wendtner, T. Chagorova, J. de la Serna, M. Dilhuydy, T. Illmer, Stephen Samuel Opat, C. Owen, O. Samoylova, K. Kreuzer, S. Stilgenbauer, H. Döhner, A. Langerak, M. Ritgen, M. Kneba, E. Asikanius, K. Humphrey, M. Wenger, M. Hallek   +22 more
semanticscholar   +1 more source

Tyrosine–Chlorambucil Conjugates Facilitate Cellular Uptake through L-Type Amino Acid Transporter 1 (LAT1) in Human Breast Cancer Cell Line MCF-7

International Journal of Molecular Sciences, 2020
l-type amino acid transporter 1 (LAT1) is an amino acid transporter that is overexpressed in several types of cancer and, thus, it can be a potential target for chemotherapy.
Piman Pocasap, N. Weerapreeyakul, Juri M. Timonen, Juulia Järvinen, J. Leppänen, Jussi Kärkkäinen, J. Rautio   +6 more
semanticscholar   +1 more source

Pilot trial of fk 506 in the management of steroid-resistant nephrotic syndrome [PDF]

, 1993
Seven patients with steroid-resistant nephrotic syndrome were treated with FK 506 monotherapy. Four patients were children with focal sclerosing glomerulonephritis (FSGS).
Ellis, D, Igdal, H, McCalley, J, Shapiro, R, Shapiro, R, Starzl, TE, Starzl, TE, Starzl, TE, Tzakis, A, Tzakis, A   +9 more
core   +1 more source

Chlorambucil combination therapy in refractory serpiginous choroiditis: A cure?

American Journal of Ophthalmology Case Reports, 2021
Purpose: To find a remedy for serpiginous choroiditis refractory to oral prednisone and chlorambucil treatment. Observations: Eight eyes of four patients (all female) with advanced macular involvement secondary to serpiginous choroiditis were included in
Arash Maleki, Anapatricia Maldonado Cerda, Cristina M. Garcia, Mike Zein, Ambika Manhapra, C. Stephen Foster   +5 more
doaj  

Azathioprine, cyclophosphamide and chlorambucil

Baillière's Clinical Rheumatology, 1990
Immunosuppressive agents serve a major role in the management of once-fatal conditions such as the systemic necrotizing vasculitides, but they are also being used in more common, chronic inflammatory disorders such as rheumatoid arthritis. The drugs are all capable of reducing cell division but they differ in their modes of action.
Luqmani, R, Palmer, R, Bacon, P
openaire   +3 more sources

Chronic lymphocytic leukaemia: Up-dated recommendations on diagnosis and treatment [PDF]

, 2004
Diagnosis and treatment of chronic lymphatic leukaemia (CLL) are currently undergoing great change. New knowledge of prognosis factors and the numerous new therapeutic procedures now available, such as purine analogues, high-dose treatment and monoclonal
Bergmann, M., Emmerich, B., Hallek, M.
core   +1 more source