Evaluation of the In Vitro Synergistic Activity of Ceftazidime/Avibactam Against <i>Stenotrophomonas maltophilia</i> Strains in Planktonic and Biofilm Cell Cultures. [PDF]
Damar-Çelik D +5 more
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A ratiometric electrochemical sensor based on Cu@Ni/MWCNTs for detection of chloramphenicol
Xiaoxue Liu +6 more
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Engineering a High-Fidelity MAD7 Variant with Enhanced Specificity for Precision Genome Editing via CcdB-Based Bacterial Screening. [PDF]
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Geographic and Behavioral Determinants of Typhoid and Antimicrobial Resistance in Children Across Urban, Rural, and Nomadic Populations of Punjab, Pakistan. [PDF]
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Distribution and antibiotic resistance patterns of airborne staphylococci in urban environments of Delhi, India. [PDF]
Kumari H +3 more
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Intraventricular Chloramphenicol
Pediatric Neurosurgery, 1978Very high intraventricular chloramphenicol levels can be obtained if the standard systemic dose is supplemented with a small intraventricular dose. Chloramphenicol sodium succinate can be hydrolyzed to the microbiologically active chloramphenicol in the ventricular fluid.
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In a recent report describing chloramphenicol pharmacokinetics1 it was stated that patients changing from intravenous to oral administration of the antibiotic exhibited prolonged half-life (t½ = 6.5 ± 2.5 [SD] hours) compared with values obtained during intravenous administration ( t½ = 4.0 ± 1.4 [SD] hours).
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Inactivation of Chloramphenicol by Chloramphenicol-Resistant Bacteria
Journal of Pharmaceutical Sciences, 1964Virtually all (94.5 per cent of 110) chloramphenicol-resistant strains of Sbigella, Escherichia , and Staphylococcus isolated from clinical cases caused significant inactivation of the antibiotic, but none of the 29 resistant pseudomonads did so. None of the 235 clinically isolated sensitive strains, representing five genera, inactivated the drug ...
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Clinical Pharmacokinetics of Chloramphenicol and Chloramphenicol Succinate
Clinical Pharmacokinetics, 1984In recent years there has been a renewal of interest in chloramphenicol, predominantly because of the emergence of ampicillin-resistant Haemophilus influenzae, the leading cause of bacterial meningitis in infants and children. Three preparations of chloramphenicol are most commonly used in clinical practice: a crystalline powder for oral administration,
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