Results 31 to 40 of about 244,019 (334)

New Chloramphenicol Derivatives with a Modified Dichloroacetyl Tail as Potential Antimicrobial Agents

Antibiotics, 2021
To combat the dangerously increasing pathogenic resistance to antibiotics, we developed new pharmacophores by chemically modifying a known antibiotic, which remains to this day the most familiar and productive way for novel antibiotic development.
Artemis Tsirogianni, Georgia G. Kournoutou, Anthony Bougas, Eleni Poulou-Sidiropoulou, George Dinos, Constantinos M. Athanassopoulos   +5 more
doaj   +1 more source

Clinical features and management of ocular lesions after stings by hymenopteran insects

Indian Journal of Ophthalmology, 2014
We describe the ocular alterations and the management after stings from Hymenopteran insects. In all the five patients, the insect was identified as bee.
K S Siddharthan, Anita Raghavan, R Revathi   +2 more
doaj   +1 more source

Site-specific incorporation of phosphotyrosine using an expanded genetic code. [PDF]

, 2017
Access to phosphoproteins with stoichiometric and site-specific phosphorylation status is key to understanding the role of protein phosphorylation.
Allison Wong, Bing Yang, C Fan, C Hoppmann, Christian Hoppmann, CS Tan, DB Johnson, DT Rogerson, H-G Chao, HS Park, J Xie, JJ Ottesen, JK Takimoto, JP Oza, Kevan M Shokat, L Wang, Lei Wang, M Jbara, MK Tarrant, NL Pirman, P Blume-Jensen, PV Hornbeck, R Serwa, R Yau, RA Chong, S George, SG Julien, Shuwei Li, SJ Humphrey, SW Santoro, T Hunter, T Wauer, Tony Hunter, VK Lacey, WA Lim, Z Chen, Z Xiang   +36 more
core   +1 more source

THE USAGE COMPARISON OF CEFTRIAXONE AND CHLORAMPHENICOL FOR TYPHOID FEVER TREATMENT: AN EVIDENCE BASED CASE REPORT

Indonesian Journal of Tropical and Infectious Disease, 2017
Typhoid fever is a disease caused by the gram-negative bacterium Salmonella typhi. Since its introduction in 1949, chloramphenicol has become the first-line treatment of typhoid fever for decades.
Jeffry Adijaya Susatyo
doaj   +1 more source

Recent Trends in Synthesis of Chloramphenicol New Derivatives

Antibiotics, 2021
Chloramphenicol (CAM), the bacteriostatic broad-spectrum antibiotic, isolated from Streptomyces venezuelae during the “golden era” of antibiotic discovery, nowadays has limited clinical potential due to adverse side effects and frequent antimicrobial ...
Anna N. Tevyashova
doaj   +1 more source

In vitro susceptibility of 120 strains of Neisseria gonorrhoeae isolated in Kyrghyzstan. [PDF]

, 2002
BACKGROUND: The World Health Organization has established a worldwide program for gonococcal antimicrobial surveillance, but so far no data on gonococcal susceptibility in Central Asia are available.
Boireaux, C, Danilenko, N V, Dorlencourt, F, Legros, D, Sednaoui, P   +4 more
core   +2 more sources

The Gathering Storm: Is Untreatable Typhoid Fever on the Way?

mBio, 2018
Klemm et al. (mBio 9:e00105-18, 2018, https://doi.org/10.1128/mBio.00105-18) present comprehensive antibiotic sensitivity patterns and genomic sequence data on Salmonella enterica serovar Typhi blood culture isolates from typhoid fever cases during an ...
Myron M. Levine, Raphael Simon
doaj   +1 more source

Adverse Outcomes Associated with Unscrupulous Ocular Use of Topical Chloramphenicol: A Case Report and Brief Review of Literature

TNOA Journal of Ophthalmic Science and Research
Topical chloramphenicol is a broad-spectrum, cost-effective antibiotic commonly used for superficial ocular and eyelid infections, especially in the low- and middle-income countries.
Sahebaan Sethi, Aditya Sethi
doaj   +1 more source

Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome

Antibiotics, 2021
Chloramphenicol (CHL) is a ribosome-targeting antibiotic that binds to the peptidyl transferase center (PTC) of the bacterial ribosome and inhibits peptide bond formation.
Chih-Wei Chen, Julia A. Pavlova, Dmitrii A. Lukianov, Andrey G. Tereshchenkov, Gennady I. Makarov, Zimfira Z. Khairullina, Vadim N. Tashlitsky, Alena Paleskava, Andrey L. Konevega, Alexey A. Bogdanov, Ilya A. Osterman, Natalia V. Sumbatyan, Yury S. Polikanov   +12 more
doaj   +1 more source

Antimicrobial Resistance in Human and Animal Pathogens in Zambia, Democratic Republic of Congo, Mozambique and Tanzania: An Urgent Need of a Sustainable Surveillance System. [PDF]

, 2013
A review of the published and unpublished literature on bacterial resistance in human and animals was performed. Sixty-eight articles/reports from the Democratic Republic of Congo (DRC), Mozambique, Tanzania and Zambia were reviewed.
Matee, Mecky, Mshana, Stephen E, Rweyemamu, Mark   +2 more
core   +1 more source