Results 61 to 70 of about 242,404 (349)
Advanced Science, EarlyView.Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao +16 more
wiley +1 more source
Microbiology Indonesia, 2014 Microbial resistance to antibiotic is a major problem in the treatment of infectious diseases. The purpose ofthis study was to identification the role of CAT enzyme for early detection of chloramphenicol resistant.
doaj +1 more source
Glutamate-pantothenate pathway promotes antibiotic resistance of Edwardsiella tarda
Frontiers in Microbiology, 2023 Although cellular metabolic states have been shown to modulate bacterial susceptibility to antibiotics, the interaction between glutamate (Glu) and chloramphenicol (CAP) resistance remains unclear because of the specificity of antibiotics and bacteria ...
Bei-bei Yan +10 more
doaj +1 more source
Metabolic properties of the products of mitochondrial protein synthesis in HeLa cells [PDF]
, 1977 The metabolic behavior of the mitochondrial protein synthesis products has been investigated in HeLa cells. Particular attention was given to the four major electrophoretic components (designated as Nos. 2, 3, 5, and 8) of the 10 previously identified as
Attardi, Giuseppe, Costantino, Paolo
core
Advanced Science, EarlyView.Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang +11 more
wiley +1 more source
Molecules, 2022 A simple and label-free electrochemical aptasensor was developed for ultra-sensitive determination of chloramphenicol (CAP) based on a 2D transition of metal carbides (MXene) loaded with gold nanoparticles (AuNPs). The embedded AuNPs not only inhibit the
Jing Yang +8 more
doaj +1 more source
Treatment of adult Valcheta frogs Pleurodema somuncurense for chytrid fungus [PDF]
, 2018 SUMMARY: Treatment of an ex-situ colony of Valcheta frog with chloramphenicol solution was not successful in eliminating chytrid fungus.Fil: Arellano, Maria Luz. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo.
Arellano, Maria Luz +6 more
core
Antimicrobial susceptibility of Neisseria gonorrheae strains in three regions of Armenia [PDF]
, 2007 OBJECTIVE: There are no data available on gonococcal susceptibility in the Caucasus region. We aimed to determine in vitro antimicrobial susceptibility of Neisseria gonorrheae in Armenia in order to update the national treatment protocol.
Borisenko +6 more
core +2 more sources
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Reporter constructs with low background activity utilizing the cat gene [PDF]
, 1992 Reporter plasmids utilizing the cat gene for the analysis of promoter and enhancer sequences in vertebrate cells, were constructed. These plasmids minimize the background of transcription derived from cryptic promoters or cryptic regulatory elements ...
Andrea Schmidt +11 more
core +1 more source