Results 41 to 50 of about 257,491 (265)

Research on improving the durability performance of damaged concrete with mineral admixtures

Engineering Reports
Concrete can be damaged under long‐term chloride ion action. This article uses mineral admixtures to repair the damaged concrete, and then conducts durability performance tests.
Jing Jing, Shuai Liu, Chunhui Guo, Baolin Guo   +3 more
doaj   +1 more source

Chloride ions in health and disease

Bioscience Reports
Abstract Chloride is a key anion involved in cellular physiology by regulating its homeostasis and rheostatic processes. Changes in cellular Cl− concentration result in differential regulation of cellular functions such as transcription and translation, post-translation modifications, cell cycle and proliferation, cell volume, and pH ...
Satish K. Raut, Kulwinder Singh, Shridhar Sanghvi, Veronica Loyo-Celis, Liyah Varghese, Ekam R. Singh, Shubha Gururaja Rao, Harpreet Singh   +7 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Effect of Micro-Cracks on Chloride Ion Diffusion in Concrete Based on Stochastic Aggregate Approach

Buildings
For concrete structures in offshore areas, chloride ion erosion is one of the main factors affecting durability. It is crucial to evaluate the chloride ion permeability resistance of concrete structures.
Qianfan Yang, Yuching Wu, Peng Zhi, Peng Zhu   +3 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Polarization and charge transfer in the hydration of chloride ions [PDF]

The Journal of Chemical Physics, 2010
A theoretical study of the structural and electronic properties of the chloride ion and water molecules in the first hydration shell is presented. The calculations are performed on an ensemble of configurations obtained from molecular dynamics simulations of a single chloride ion in bulk water. The simulations utilize the polarizable AMOEBA force field
Zhao, Zhen, Rogers, David M., Beck, Thomas L.   +2 more
openaire   +3 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Over twenty years trend of chloride ion concentration in Lake Biwa

Journal of Limnology, 2003
Recent increase of chloride ion concentration in Lake Biwa was considered. Over the past 20 years' data at the North Basin of Lake Biwa showed that chloride ion concentration has been continuously increasing from 7.4 to 9.9 mg l-1 at 0.5 m depth from ...
Kanako ISHIKAWA, Michio KUMAGAI, Yasuaki AOTA   +2 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Multi-scale investigation of stainless-steel passivation in seawater concrete pore solution

Case Studies in Construction Materials
Stainless-steel bars can be effectively used in seawater sea sand concrete due to their excellent resistance to chloride ions, contributing to resource conservation and sustainable development.
Jiahong Wei, Quanming Fu, Duowen Chen, Xutao Wang, Wenkai Cao, Di Xu, Haibing Zheng   +6 more
doaj   +1 more source