Modulating IDO1 and TDO Inhibition Through Structural Modification of Diaryl Hydroxylamines
Diaryl hydroxylamines have emerged as promising scaffolds for targeting the tryptophan‐catabolizing enzymes indoleamine 2,3‐dioxygenase 1 (IDO1) and tryptophan 2,3‐dioxygenase (TDO), key drivers of tumor immune escape. Building on the reported dual IDO1/TDO inhibitory activity of O‐((3,5‐difluorophenyl)(phenyl)methyl)hydroxylamine, a series of diaryl ...
Angeliki S. Foscolos +8 more
wiley +1 more source
Pyrolysis Reactions of (2-Chloroethyl)benzene. [PDF]
Jarrell M +6 more
europepmc +1 more source
Nitridated Iron-Based (Nano)Materials for Environmental Remediation: Synthesis, Characterization, and Performance. [PDF]
Gong L +5 more
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Two-step coupled photoelectrochemical chlorination and oxygenation of C(sp<sup>3</sup>)-H bonds mediated by chlorine radicals over a modified BiVO<sub>4</sub> photoanode. [PDF]
Yang W +8 more
europepmc +1 more source
Determination of chlorinated hydrocarbons in water using highly sensitive mid-infrared sensor technology. [PDF]
Lu R +7 more
europepmc +1 more source
Optimization of soil conditions for bioremediation in chemically pretreated soil: site characterization [PDF]
Grotenhuis, J.T.C. +2 more
core
Evaluating human health risk assessment tools for contaminated soil: a comparative review. [PDF]
Lupu R, Cocarta DM, Verginelli I.
europepmc +1 more source
Target and Non-Target Analysis of Polycyclic Aromatic Hydrocarbons and Emerging Aromatic Contaminants in Outdoor Dust from a Petrochemical-Impacted Residential Area. [PDF]
Si Y +6 more
europepmc +1 more source
Heating Effect on the Liquid-Crystalline Octakis(hexylthio)zinc(II) Phthalocyanine Thin Film Sensor for the Detection of Chlorinated Hydrocarbon Vapors and Interaction Mechanism Analysis Using Density Functional Theory. [PDF]
Özer Z +5 more
europepmc +1 more source
FACTORS INFLUENCING ATMOSPHERIC COMPOSITION OVER SUB-ARCTIC NORTH-AMERICA DURING SUMMER [PDF]
BLAKE, DR +7 more
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