Results 51 to 60 of about 157 (132)

Analysis of prostate-specific antigen transcripts in chimpanzees, cynomolgus monkeys, baboons, and African green monkeys. [PDF]

open access: yesPLoS ONE, 2014
The function of prostate-specific antigen (PSA) is to liquefy the semen coagulum so that the released sperm can fuse with the ovum. Fifteen spliced variants of the PSA gene have been reported in humans, but little is known about alternative splicing in ...
James N Mubiru   +9 more
doaj   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang   +19 more
wiley   +1 more source

Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health

open access: yesRedox Biology, 2016
Blood based bioenergetic profiling strategies are emerging as potential reporters of systemic mitochondrial function; however, the extent to which these measures reflect the bioenergetic capacity of other tissues is not known. The premise of this work is
Daniel J. Tyrrell   +4 more
doaj   +1 more source

No evidence for sylvatic cycles of chikungunya, dengue and Zika viruses in African green monkeys (Chlorocebus aethiops sabaeus) on St. Kitts, West Indies

open access: yesParasites & Vectors, 2020
Background Dengue, chikungunya and Zika viruses (DENV, CHIKV and ZIKV) are transmitted in sylvatic transmission cycles between non-human primates and forest (sylvan) mosquitoes in Africa and Asia.
Matthew John Valentine   +14 more
doaj   +1 more source

Health Correlates of Extended Longevity in Captive Ring‐Tailed Lemurs (Lemur catta)

open access: yesAmerican Journal of Primatology, Volume 87, Issue 12, December 2025.
Male and female ring‐tailed lemurs exhibit distinct patterns of age‐related change in certain serum chemistry markers. Photo by David Haring. ABSTRACT Captive primates maintained at accredited institutions can live extraordinarily long lives and, as a result, are useful models for understanding the physiology of aging. Many institutions monitor primate
Ruby L. Mustill   +4 more
wiley   +1 more source

IL-6 is Upregulated in Late-Stage Disease in Monkeys Experimentally Infected with Trypanosoma brucei rhodesiense

open access: yesClinical and Developmental Immunology, 2013
The management of human African trypanosomiasis (HAT) is constrained by lack of simple-to-use diagnostic, staging, and treatment tools. The search for novel biomarkers is, therefore, essential in the fight against HAT.
Dawn Nyawira Maranga   +5 more
doaj   +1 more source

Genetic evidence for the role of non-human primates as reservoir hosts for human schistosomiasis.

open access: yesPLoS Neglected Tropical Diseases, 2020
BackgroundSchistosomiasis is a chronic parasitic disease, that affects over 207 million people and causes over 200,000 deaths annually, mainly in sub-Saharan Africa.
Tadesse Kebede   +5 more
doaj   +1 more source

Spatial molecular characterization of early Alzheimer's disease neuropathology in aged Vervet monkeys

open access: yesAlzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Vervets (Chlorocebus aethiops) are non‐human primates in which we previously demonstrated brain amyloid b (Ab) deposition and phosphorylated tau associations with reduced brain volume, glucose metabolism, and gait speed but lacking true neurofibrillary tangles (NFTs).
Caitlin S Latimer   +10 more
wiley   +1 more source

Joint MiRNA/mRNA expression profiling reveals changes consistent with development of dysfunctional corpus luteum after weight gain. [PDF]

open access: yesPLoS ONE, 2015
Obese women exhibit decreased fertility, high miscarriage rates and dysfunctional corpus luteum (CL), but molecular mechanisms are poorly defined. We hypothesized that weight gain induces alterations in CL gene expression.
Andrew P Bradford   +10 more
doaj   +1 more source

Social frailty and brain health in nonhuman primates: Relationships between social behavior, neuroanatomy, and CSF biomarkers relevant to Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue S2, December 2025.
Abstract Background In humans, age‐related accumulations of physical deficits are often characterized by frailty indices, which predict increased risk for neurodegeneration characteristic of Alzheimer's disease (AD). However, social capabilities also may diminish, with considerable variation in inter‐individual trajectories of decline and AD risk ...
Brett M. Frye   +11 more
wiley   +1 more source

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