Results 1 to 10 of about 2,336,793 (302)

First report of novel single nucleotide polymorphisms (SNPs) and genetic characteristics of the prion-like protein gene (PRND) in cynomolgus monkeys [PDF]

Frontiers in Veterinary Science
Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases caused by misfolded prion protein. The prion-like protein (Doppel), encoded by the prion-like protein gene (PRND), is linked to neurodegeneration and TSE susceptibility.
Chung-Bae Oh, Chung-Bae Oh, Chung-Bae Oh, Da-In Choi, Da-In Choi, Byung-Hoon Jeong, Byung-Hoon Jeong   +6 more
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Application and prospects of veterinary diagnostic techniques in laboratory monkeys [PDF]

Frontiers in Veterinary Science
As the non-human primate models with the closest genetic relationship to humans, laboratory monkeys are indispensable in life sciences research, drug development, and biological product evaluation.
Zhengjia Zhang, Diangang Han, Qiujiang Wei, Xuewei Fu, Yongqing Yan, Dandan Li, Jige Xin   +6 more
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Establishment of porcine and monkey colonic organoids for drug toxicity study

Cell Regeneration, 2021
Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses.
Haonan Li, Yalong Wang, Mengxian Zhang, Hong Wang, Along Cui, Jianguo Zhao, Weizhi Ji, Ye-Guang Chen   +7 more
doaj   +1 more source

A draft map of rhesus monkey tissue proteome for biomedical research. [PDF]

PLoS ONE, 2015
Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases because of its manageable size and genetic and proteomic similarities with humans, proteomic research using rhesus monkeys still remains ...
Jin-Gyun Lee, Kimberly Q McKinney, Yong-Yook Lee, Hae-Na Chung, Antonis J Pavlopoulos, Kook Y Jung, Woong-Ki Kim, Marcelo J Kuroda, David K Han, Sunil Hwang   +9 more
doaj   +1 more source

Sequence Analysis of Macaca mulatta TRIM4 and Its Role in the Interferon Pathway

Frontiers in Veterinary Science, 2022
Monkey diseases are becoming increasingly severe, and some may be transmitted to humans through direct and indirect contact. Innate immunity is the first line of defense against foreign microorganisms.
Mengmeng Zhao, Huawei Li, Hang Zhang, Huiyang Sha, Liangzong Huang, Ruining Wang   +5 more
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Heterogeneity of circulating CD4+CD8+ double-positive T cells characterized by scRNA-seq analysis and trajectory inference

Scientific Reports, 2022
The frequency of CD4+CD8+ double-positive (DP) T cells is highly associated with a variety of diseases. Recently, we used high-throughput single-cell RNA sequencing to show that circulating DP T cells in cynomolgus monkeys comprise nine heterogeneous ...
Sung Min Choi, Hi Jung Park, Eun A Choi, Kyeong Cheon Jung, Jae Il Lee   +4 more
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Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging

Frontiers in Cell and Developmental Biology, 2021
Vascular aging is a potent driver of cardiovascular and cerebrovascular diseases. Vascular aging features cellular and functional changes, while its molecular mechanisms and the cell heterogeneity are poorly understood.
Fei Ge, Qi Pan, Yue Qin, Mengping Jia, Chengchao Ruan, Xiangxiang Wei, Qing Jing, Xiuling Zhi, Xinhong Wang, Lindi Jiang, Elena Osto, Jieyu Guo, Dan Meng   +12 more
doaj   +1 more source

The basic reproductive ratio of the 2022 outbreak of the monkey pox virus disease for the United Kingdom, Canada, Brazil, the United Arab Emirates, and Nigeria

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background A recent outbreak of the monkey pox virus disease (MPVD) started to spread over the world before the second half of the 2022 year. This outbreak of the monkey pox virus disease is known as the 2022 outbreak of the monkey pox virus disease. The
Marwan Al-Raeei
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CT anatomy and normal radiography of the skull of the Rhesus monkey (Macaca mulatta)

Veterinary Medicine and Science, 2023
Background Considering the relationship between human morphology and physiology with the Rhesus monkey, this animal is the most prominent species of laboratory primate for human and animal health research.
Ali Reza Vajhi, Sarang Soroori, Reihaneh Soflaei, Omid Zehtabvar, Seyyed Hossein Modarres Tonekabony, Iman Memarian   +5 more
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Brain Region- and Age-Dependent 5-Hydroxymethylcytosine Activity in the Non-Human Primate

Frontiers in Aging Neuroscience, 2022
Because of the difficulty in collecting fresh brains of humans at different ages, it remains unknown how epigenetic regulation occurs in the primate brains during aging.
Yanru Xu, Liying Zhong, Huixian Wei, Yuwei Li, Jiaxiang Xie, Leijie Xie, Xiusheng Chen, Xiangyu Guo, Peng Yin, Shihua Li, Junwei Zeng, Xiao-Jiang Li, Li Lin   +12 more
doaj   +1 more source