Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]
, 2018 BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.
core +2 more sources
Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing
Protein & Cell, 2020 Many human genetic diseases, including Hutchinson-Gilford progeria syndrome (HGPS), are caused by single point mutations. HGPS is a rare disorder that causes premature aging and is usually caused by a de novo point mutation in the LMNA gene. Base editors
Fang Wang +17 more
doaj +1 more source
Sequence Analysis of APOE Gene Across Mammalian Species in Thailand
Science Technology and Engineering Journal (STEJ), 2021 The current study utilized five mammalian species, including rhesus monkey (Macaca mulatta), Thai Bangkaew dog (Canis lupus familiaris), Thai domestic cat (Felis catus), tiger (Panthera tigris) and Thai domestic rabbit (Oryctolagus cuniculus) to survey ...
Dechawut Bunyaluk +2 more
doaj +1 more source
Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques [PDF]
, 2016 Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of lymphoid proliferations that occur in the setting of depressed T-cell function due to immunosuppressive therapy used following solid organ transplantation, hematopoietic ...
Aron Badin, R. +12 more
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Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds [PDF]
, 2017 Background Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features.
Evans, K M +4 more
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Germline transmission in transgenic Huntington's disease monkeys [PDF]
Theriogenology, 2015 Transgenic nonhuman primate models are an increasingly popular model for neurologic and neurodegenerative disease because their brain functions and neural anatomies closely resemble those of humans. Transgenic Huntington's disease monkeys (HD monkeys) developed clinical features similar to those seen in HD patients, making the monkeys suitable for a ...
Sean, Moran +7 more
openaire +2 more sources
Increased sampling reveals novel lineages of Entamoeba: consequences of genetic diversity and host specificity for taxonomy and molecular detection. [PDF]
, 2011 To expand the representation for phylogenetic analysis, ten additional complete Entamoeba small-subunit rRNA gene sequences were obtained from humans, non-human primates, cattle and a tortoise. For some novel sequences no corresponding morphological data
Alfellani, Mohammed +7 more
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Radiolabeling human peripheral blood stem cells for positron emission tomography (PET) imaging in young rhesus monkeys. [PDF]
, 2013 These studies focused on a new radiolabeling technique with copper ((64)Cu) and zirconium ((89)Zr) for positron emission tomography (PET) imaging using a CD45 antibody.
Cherry, Simon R +3 more
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Monkey hybrid stem cells develop cellular features of Huntington's disease
BMC Cell Biology, 2010 Background Pluripotent stem cells that are capable of differentiating into different cell types and develop robust hallmark cellular features are useful tools for clarifying the impact of developmental events on neurodegenerative diseases such as ...
Lorthongpanich Chanchao +9 more
doaj +1 more source
Phylogenetic relationships of Cryptosporidium parasites based on the 70- kilodalton heat shock protein (HSP70) gene [PDF]
, 2000 We have characterized the nucleotide sequences of the 70-kDa heat shock protein (HSP70) genes of Cryptosporidium baileyi, C. felis, C. meleagridis, C. muris, C. serpentis, C. wrairi, and C. parvum from various animals.
Sulaiman, I. +4 more
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