Results 41 to 50 of about 2,336,793 (302)

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

open access: yesAdvanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal   +21 more
wiley   +1 more source

Establishment of an induced pluripotent stem cell line (cmESF-iPSC-C3) from cynomolgus monkey ear fibroblasts

open access: yesStem Cell Research
Induced pluripotent stem cells (iPSCs) derived from cynomolgus monkey (crab-eating macaque) ear fibroblasts offer a minimally invasive and ethically acceptable source of cells for autologous therapies and preclinical research.
Seo-Hyun An   +6 more
doaj   +1 more source

Survival of Human Induced Pluripotent Stem Cell–Derived Midbrain Dopaminergic Neurons in the Brain of a Primate Model of Parkinson's Disease

open access: yesJournal of Parkinson’s Disease, 2011
Before induced pluripotent stem cells (iPSCs) can be used to treat neurologic diseases, human iPSC-derived neural cells must be analyzed in the primate brain.
Tetsuhiro Kikuchi   +8 more
doaj   +1 more source

Nanoamphizymes: Self‐Assembled Amphiphilic Enzymatic Nanomaterials for High‐Performance Biocatalysis and Biosensing

open access: yesAdvanced Functional Materials, EarlyView.
An amphiphilic GOx nanoamphizyme was constructed by covalently introducing hydrophobic PPNI linkers onto GOx, enabling spontaneous self‐assembly into tunable nanoparticles. Mild crosslinking further stabilized the assemblies and enhanced catalytic performance and stability.
Yuan‐Hao Hsiao   +4 more
wiley   +1 more source

[News Clip: Monkey]

open access: yes, 1959
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about a monkey that mysteriously came into the neighborhood.
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

A Robust Single Primate Neuroepithelial Cell Clonal Expansion System for Neural Tube Development and Disease Studies

open access: yesStem Cell Reports, 2016
Developing a model of primate neural tube (NT) development is important to promote many NT disorder studies in model organisms. Here, we report a robust and stable system to allow for clonal expansion of single monkey neuroepithelial stem cells (NESCs ...
Xiaoqing Zhu   +13 more
doaj   +1 more source

Live Viral Vaccine Neurovirulence Screening: Current and Future Models

open access: yesVaccines, 2021
Live viral vaccines are one of the most successful methods for controlling viral infections but require strong evidence to indicate that they are properly attenuated.
Corey May Fulton, Wendy J. Bailey
doaj   +1 more source

Germline transmission in transgenic Huntington's disease monkeys [PDF]

open access: yesTheriogenology, 2015
Transgenic nonhuman primate models are an increasingly popular model for neurologic and neurodegenerative disease because their brain functions and neural anatomies closely resemble those of humans. Transgenic Huntington's disease monkeys (HD monkeys) developed clinical features similar to those seen in HD patients, making the monkeys suitable for a ...
Sean, Moran   +7 more
openaire   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

open access: yesAdvanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

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