Results 51 to 60 of about 67,779 (299)

Human – monkey interaction on a University campus in Nigeria: An avenue for zoonotic disease transmission at the human wildlife interface? [PDF]

, 2017
Monkeys are potential sources of infectious diseases to humans. Mona monkeys frequently gain access to human dwellings within the University of Lagos campus.
Olaleru, F, Olugasa, B, Oladiti, F, Ogunro, B   +3 more
core   +2 more sources

Assessing the microbial diversity and proximate composition of smoked-fermented bushmeat from four different bushmeat samples

BioTechnologia
The ever-increasing demand for wildlife-derived raw or processed meat commonly known as bushmeat, has been identified as one of the critical factors driving the emergence of infectious diseases.
Afia Sakyiwaa Amponsah, Gloria Mathanda Ankar-Brewoo, Herman Erick Lutterodt, Isaac Williams Ofosu   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Survival of Human Induced Pluripotent Stem Cell–Derived Midbrain Dopaminergic Neurons in the Brain of a Primate Model of Parkinson's Disease

Journal of Parkinson’s Disease, 2011
Before induced pluripotent stem cells (iPSCs) can be used to treat neurologic diseases, human iPSC-derived neural cells must be analyzed in the primate brain.
Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Hirotaka Onoe, Takuya Hayashi, Toshiyuki Kawasaki, Hidemoto Saiki, Susumu Miyamoto, Jun Takahashi   +8 more
doaj   +1 more source

Live Viral Vaccine Neurovirulence Screening: Current and Future Models

Vaccines, 2021
Live viral vaccines are one of the most successful methods for controlling viral infections but require strong evidence to indicate that they are properly attenuated.
Corey May Fulton, Wendy J. Bailey
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Monkey troop sizes [PDF]

<p>This dataset is a synthesis of publicised data on monkey troop sizes. It is important to monitor the biodiversity and prevalence of monkeys as many of them are ICUN redlist endangered species and are particularly affected by climate change and ...
Meszka, Filip
core   +1 more source

Dilated cardiomyopathy in spider monkey (Ateles chamek, Humboldt, 1812) [PDF]

, 2019
Non-human primates are routinely studied and managed in zoos, conservation breeding centers, and research centers, but there is currently limited information regarding diseases that can affect these animals.
Jonimar Pereira Paiva, Fernando Troccoli, Andressa Kagohara, Alessandro Galhões, Bárbara Souza Neil Magalhães, Mário dos Santos Filho, Heloisa Helena de Campos Coutinho Chaves, Daniel de Almeida Balthazar   +7 more
core   +2 more sources

Establishment of an induced pluripotent stem cell line (cmESF-iPSC-C3) from cynomolgus monkey ear fibroblasts

Stem Cell Research
Induced pluripotent stem cells (iPSCs) derived from cynomolgus monkey (crab-eating macaque) ear fibroblasts offer a minimally invasive and ethically acceptable source of cells for autologous therapies and preclinical research.
Seo-Hyun An, Ji-Yeon Kim, Xing Zhen, Gyu-Seo Bae, Young-Hyun Kim, Sang-Je Park, Jong-Hee Lee   +6 more
doaj   +1 more source