Experimental Yellow Fever in the Squirrel Monkey (Saimiri spp.): Hematological, Biochemical, and Immunological Findings [PDF]
Between 2016 and 2018, Brazil experienced the largest sylvatic epidemic of yellow fever virus (YFV). Despite to the magnitude and rapid spread of the epidemic, little is known about YFV dispersion.
Maria Nazaré O. Freitas +13 more
core +1 more source
Characterization, isolation, and culture of spermatogonial stem cells in Macaca fascicularis
Spermatogonial stem cells (SSCs) have great applications in both reproductive and regenerative medicine. Primates including monkeys are very similar to humans with regard to physiology and pathology. Nevertheless, little is known about the isolation, the
Guo-Ping Mao +6 more
doaj +1 more source
Chemotherapy of second stage human African trypanosomiasis : comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys [PDF]
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the second stage (central nervous system [CNS]) of ...
Wang, Michael Z. +41 more
core +1 more source
A REVIEW ON MONKEY POX DISEASE
After the disastrous COVID-19 pandemic, now, monkey pox has spreaded its legs all over the world. Disease originated in Africa but its outbreak occurred in 89 countries since January 2022. As per the World Health Organization report, in between January 1, 2022, and August 10, 2022, 27,814 confirmed cases and 11 deaths occurred across 89 countries ...
PRIYANKA KAMARIA, SOURAV GUHA
openaire +1 more source
Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys
Tauopathy, characterized by the hyperphosphorylation and accumulation of the microtubule-associated protein tau, and the accumulation of Aβ oligomers, constitute the major pathological hallmarks of Alzheimer’s disease.
Zhuchi Tu +13 more
doaj +1 more source
Brainstem : neglected locus in neurodegenerative diseases [PDF]
The most frequent neurodegenerative diseases (NDs) are Alzheimer’s disease (AD), Parkinson’s disease (PD), and frontotemporal lobar degeneration associated with protein TDP-43 (FTLD–TDP).
Lea Tenenholz Grinberg +8 more
core +1 more source
[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys. [PDF]
BackgroundThe alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease.
Kenji Hashimoto +8 more
doaj +1 more source
Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
Paul C. Divis (615586) +90 more
core +1 more source
Multiplex precise base editing in cynomolgus monkeys
Due to the polygenic nature of most diseases, simultaneous correction or introduction of single nucleotide variants is needed. Here, the authors demonstrated the feasibility of multiplex base editing for polygenes disease modeling in cynomolgus monkey ...
Wenhui Zhang +18 more
doaj +1 more source

