Results 31 to 40 of about 67,538 (200)
Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys
Signal Transduction and Targeted Therapy, 2023 Tauopathy, characterized by the hyperphosphorylation and accumulation of the microtubule-associated protein tau, and the accumulation of Aβ oligomers, constitute the major pathological hallmarks of Alzheimer’s disease.
Zhuchi Tu +13 more
doaj +1 more source
[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys. [PDF]
PLoS ONE, 2008 BackgroundThe alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease.
Kenji Hashimoto +8 more
doaj +1 more source
Nature, 1960 Diseases of Laboratory Primates By Prof. Theodore C. Ruch. Pp. xxvi + 600. (Philadelphia and London: W. B. Saunders Company, 1959.) 52s. 6d.
openaire +1 more source
, 2022 Currently, Monkeypox is a threatening viral disease terminology around the world that worries the global community after the Coronavirus pandemic. Beyond the woods of central Africa, where cases were first discovered, the geographic distribution of ...
Jeyachandran, Akshay +10 more
core +1 more source
A REVIEW ON MONKEY POX DISEASE
Innovare Journal Health Sciences, 2022 After the disastrous COVID-19 pandemic, now, monkey pox has spreaded its legs all over the world. Disease originated in Africa but its outbreak occurred in 89 countries since January 2022. As per the World Health Organization report, in between January 1, 2022, and August 10, 2022, 27,814 confirmed cases and 11 deaths occurred across 89 countries ...
PRIYANKA KAMARIA, SOURAV GUHA
openaire +1 more source
Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]
, 2014 Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
Paul C. Divis (615586) +90 more
core +1 more source
Multiplex precise base editing in cynomolgus monkeys
Nature Communications, 2020 Due to the polygenic nature of most diseases, simultaneous correction or introduction of single nucleotide variants is needed. Here, the authors demonstrated the feasibility of multiplex base editing for polygenes disease modeling in cynomolgus monkey ...
Wenhui Zhang +18 more
doaj +1 more source
Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing
Protein & Cell, 2020 Many human genetic diseases, including Hutchinson-Gilford progeria syndrome (HGPS), are caused by single point mutations. HGPS is a rare disorder that causes premature aging and is usually caused by a de novo point mutation in the LMNA gene. Base editors
Fang Wang +17 more
doaj +1 more source
Sequence Analysis of APOE Gene Across Mammalian Species in Thailand
Science Technology and Engineering Journal (STEJ), 2021 The current study utilized five mammalian species, including rhesus monkey (Macaca mulatta), Thai Bangkaew dog (Canis lupus familiaris), Thai domestic cat (Felis catus), tiger (Panthera tigris) and Thai domestic rabbit (Oryctolagus cuniculus) to survey ...
Dechawut Bunyaluk +2 more
doaj +1 more source