Characterization, isolation, and culture of spermatogonial stem cells in Macaca fascicularis
Spermatogonial stem cells (SSCs) have great applications in both reproductive and regenerative medicine. Primates including monkeys are very similar to humans with regard to physiology and pathology. Nevertheless, little is known about the isolation, the
Guo-Ping Mao +6 more
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Background The pteropine orthoreovirus (PRV) was isolated from monkey (Macaca fascicularis) faecal samples collected from human-inhabited areas in Lopburi Province, Thailand. These samples were initially obtained to survey for the presence of hepatitis E
Nathamon Kosoltanapiwat +11 more
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Population dynamics of rhesus macaques and associated foamy virus in Bangladesh. [PDF]
Foamy viruses are complex retroviruses that have been shown to be transmitted from nonhuman primates to humans. In Bangladesh, infection with simian foamy virus (SFV) is ubiquitous among rhesus macaques, which come into contact with humans in diverse ...
Andreina Pacheco, M +19 more
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Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys
Tauopathy, characterized by the hyperphosphorylation and accumulation of the microtubule-associated protein tau, and the accumulation of Aβ oligomers, constitute the major pathological hallmarks of Alzheimer’s disease.
Zhuchi Tu +13 more
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Diseases of Laboratory Primates By Prof. Theodore C. Ruch. Pp. xxvi + 600. (Philadelphia and London: W. B. Saunders Company, 1959.) 52s. 6d.
openaire +1 more source
Canine distemper virus neutralization activity is low in human serum and it is sensitive to an amino acid substitution in the hemagglutinin protein [PDF]
© 2015 Elsevier Inc.Serum was analyzed from 146 healthy adult volunteers in eastern Africa to evaluate measles virus (MV) and canine distemper virus (CDV) neutralizing antibody (nAb) prevalence and potency.
Allen, S +13 more
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[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys. [PDF]
BackgroundThe alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease.
Kenji Hashimoto +8 more
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Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model [PDF]
Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to artemisinin-based combination therapies.
Baro, Nicholas +14 more
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Vaccine innovation, translational research and the management of knowledge accumulation [PDF]
What does it take to translate research into socially beneficial technologies like vaccines? Current policy that focuses on expanding research or strengthening incentives overlooks how the supply and demand of innovation is mediated by problem-solving ...
Andre +86 more
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Multiplex precise base editing in cynomolgus monkeys
Due to the polygenic nature of most diseases, simultaneous correction or introduction of single nucleotide variants is needed. Here, the authors demonstrated the feasibility of multiplex base editing for polygenes disease modeling in cynomolgus monkey ...
Wenhui Zhang +18 more
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